Tetanus and Diphtheria Toxoids Adsorbed (Td) is a vaccine indicated for active immunization for the prevention of tetanus and diphtheria. This vaccine is approved for use in persons 7 years of age and older.
The Advisory Committee on Immunization Practices (ACIP) recommends that all appropriate adults >65 years receive a routine Td booster vaccination every 10 years.1
For appropriate adults 19 to 64 years, substitute 1-time dose of Tdap for Td booster, then boost with Td every 10 years.1 For adults aged 65 years and older who have or anticipate having close contact with an infant younger than 12 months, substitute a single dose of Tdap.1
Select Safety Information
The tetanus diphtheria vaccine is contraindicated in patients with hypersensitivity to any component of the vaccine or who have had a severe allergic reaction after a previous dose of this vaccine or any other Td vaccine.
Persons who experienced an Arthus-type hypersensitivity reaction following a prior dose of a tetanus toxoid-containing vaccine usually have high serum tetanus antitoxin levels and should not receive the Td vaccine more frequently than every 10 years, even for tetanus prophylaxis as part of wound management.
If Guillain-Barre Syndrome occurred within 6 weeks after receipt of a previous dose of tetanus toxoid-containing vaccine, the decision to give subsequent doses of the Td vaccine or any vaccine containing tetanus toxoid should be based on careful consideration of the potential benefits and possible risks.
The most common local adverse reactions associated with Td vaccine may include erythema (redness), tenderness, and swelling at the injection site. Common systemic reactions may include headache, malaise, and temperature elevations.
Vaccination with Td vaccine may not protect all individuals.
Before administering Tetanus and Diphtheria Toxoids Adsorbed, please read the Prescribing Information.
Reference: 1. Centers for Disease Control and Prevention (CDC). Recommended Immunization Schedule—United States, 2012. MMWR. 2012;61(4).
