Zoster disease information

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Disease Overview

How do patients describe zoster?

	Are zoster complications common, and what are they?
	1 in 4 zoster patients will experience 1 or more complications, some of which may be severe.^1,3 Postherpetic neuralgia Scarring Bacterial superinfection Pneumonia Cranial and motor neuron palsies Visual impairment, when eye area is involved Hearing loss, when ear are is involved 10% of zoster patients develop zoster ophthalmicus, which can lead to visual morbidity.⁶ NOT TYPICAL

What is the most important risk factor for zoster?

How do you know which patients will be affected by zoster?

What does zoster look like?

Disease information

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CDC Information

CDC=Centers for Disease Control and Prevention.

VACC-1008856-0000 09/2011, VACC-1008856-0001 10/11

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Oxman MN. Clinical manifestations of herpes zoster. In: Arvin AM, Gershon AA, eds. Varicella-Zoster Virus: Virology and Clinical Management. Cambridge, UK: Cambridge University Press; 2000:246–275.

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Katz J, Cooper EM, Walther RR, et al. Acute pain in herpes zoster and its impact on health-related quality of life. Clin Infect Dis. 2004;39(3):342–348.

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Yawn BP, Saddier P, Wollan PC, et al. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction. Mayo Clin Proc. 2007;82(11):1341–1349.

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Johnson RW. Consequences and management of pain in herpes zoster. J Infect Dis. 2002;186(suppl 1):S83–S90.

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Bowsher D. Pain, sensory change, and allodynia in postherpetic neuralgia. In: Watson CPN, Gershon AA, eds. Herpes Zoster and Postherpetic Neuralgia, 2nd Revised and Enlarged Edition. Amsterdam, The Netherlands: Elsevier Science B.V.; 2001:143–147. Pain Research and Clinical Management; vol 11.

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Pavan-Langston D. Ophthalmic zoster. In: Arvin AM, Gershon AA, eds. Varicella-Zoster Virus: Virology and Clinical Management. Cambridge, UK: Cambridge University Press; 2000:276–298.

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Centers for Disease Control and Prevention (CDC). Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2008;57(RR-5):1–30.

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Centers for Disease Control and Prevention (CDC). Population projections, United States, 2004–2030. http://wonder.cdc.gov/population-projections.html. Accessed August 10, 2010.

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Arvin AM. Varicella-zoster virus. In: Knipe DM, Howley PM, eds. Fields Virology. Vol 2. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001:2731–2767.

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Schmader KE. Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy. Clin J Pain. 2002;18(6):350–354.

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Insinga RP, Itzler RF, Pellissier JM, et al. The incidence of herpes zoster in a United States administrative database. J Gen Intern Med. 2005;20(8):748–753.

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Whitley RJ. Herpes zoster: natural history, diagnosis and therapy. In: Watson CPN, Gershon AA, eds. Herpes Zoster and Postherpetic Neuralgia, 2nd Revised and Enlarged Edition. Amsterdam, The Netherlands: Elsevier Science B.V.; 2001:65–78. Pain Research and Clinical Management; vol 11.

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Schmader K, Gnann JW Jr, Watson CP. The epidemiological, clinical, and pathological rationale for the herpes zoster vaccine. J Infect Dis. 2008;197(suppl 2):S207–S215.

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Kost RG, Straus SE. Postherpetic neuralgia—pathogenesis, treatment, and prevention. N Engl J Med. 1996;335(1):32–42.

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