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Important medical organizations
recommend vaccination for the prevention of varicella
ACIP
For all appropriate individuals who have had the
first dose ACIP recommends a 2nd
varicella vaccination.1
View information about ACIP Recommendations
AAP
"
To achieve greater levels of immunity with fewer
serosusceptible people, protection against breakthrough
varicella disease, and reduction in the number
of outbreaks occurring nationwide among school-aged
populations, a 2-dose varicella immunization strategy
is now recommended for children >12 months of age."11
View information about AAP Recommendations
AAFP
"
Two 0.5-mL doses of varicella vaccine administered
subcutaneously are recommended for children 12
months and older, adolescents, and adults without evidence
of immunity."12
View information about AAFP Recommendations
Select Safety Information
In children, adolescents, and adults monitored for
up to 42 days, the adverse effects most frequently
reported were as follows: fever, injection-site
complaints, varicella-like rash (injection site),
and varicella-like rash (generalized).
In a clinical
trial involving children who received 2 doses of
VARIVAX 3 months apart, the incidence
of injection-site clinical complaints (primarily
erythema and swelling) observed in the first 4
days following vaccination was slightly higher
post-dose
2 (overall incidence 25.4%) than post-dose 1 (overall
incidence 21.7%), whereas the incidence of systemic
clinical complaints in the 42-day follow-up period
was lower post-dose 2 (66.3%) than post-dose 1
(85.8%).
There are insufficient data to assess the
rate of protection of VARIVAX against the serious
complications
of chickenpox (eg, encephalitis, hepatitis, pneumonia),
and during pregnancy (congenital varicella syndrome).
The
duration of protection of VARIVAX is unknown;
however, long-term efficacy studies have demonstrated
continued protection up to 10 years after vaccination.
Vaccination
with VARIVAX may not result in protection of
all healthy, susceptible children,
adolescents,
and adults.
Before administering VARIVAX, please read the Prescribing
Information and
Patient Product Information.
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