{"id":1298,"date":"2025-12-22T12:35:13","date_gmt":"2025-12-22T12:35:13","guid":{"rendered":"https:\/\/www.merckvaccines.com\/mmr\/?page_id=1298"},"modified":"2026-01-08T06:41:25","modified_gmt":"2026-01-08T06:41:25","slug":"adult-efficacy","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/mmr\/adult-efficacy\/","title":{"rendered":"Adult"},"content":{"rendered":"<link rel='stylesheet' id='vivid360-hero-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/hero\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-hero\"><div class=\"vivid360-hero-container align-left align-middle ratio-70-30 horizontal desktop text-align-left has-primary-dark-color is-default-style mobile-is-overlay-style mobile-is-full-overlay mobile-is-opaque-overlay mobile-uses-custom-styles\" style=\"border-width:0;border-style:solid;border-top-left-radius:0;border-top-right-radius:0;border-bottom-right-radius:0;border-bottom-left-radius:0;--minHeight:267px;--mobileMinHeight:200px\"><div class=\"wide_screens hidden\" data-value=\"default\"><\/div><picture><source media=\"(max-width: 767px)\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/test_v2.png?w=767\"\/><source media=\"(min-width: 768px) and (max-width:1024px)\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Clinical-Data-Adult_MMRII_Banner_1128px_MAX.png?w=1024\"\/><source media=\"(min-width: 1025px) and (max-width:1440px)\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Clinical-Data-Adult_MMRII_Banner_1128px_MAX.png?w=1440\"\/><img decoding=\"async\" width=\"4700\" height=\"1012\" loading=\"lazy\" data-src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Clinical-Data-Adult_MMRII_Banner_1128px_MAX.png?w=1488\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Clinical-Data-Adult_MMRII_Banner_1128px_MAX.png?w=1488\" alt=\"\" class=\"hero-image\" style=\"--desktop-focal-x:97%;--desktop-focal-y:3%;--mobile-focal-x:0%;--mobile-focal-y:100%;--tablet-focal-x:97%;--tablet-focal-y:3%\"\/><div class=\"capoverlay-container-desktop right-bottom show custom_margin hide_mobile isMobileOverlayChecked label\" style=\"--top-margin:;--bottom-margin:8px;--left-margin:;--right-margin:16px\"><div class=\"overlay-caption-schema\">Actor Portrayal<\/div><\/div><\/picture><div class=\"hero-wrapper\"><div class=\"hero-content\"><h1 style=\"--headlineFontSize:36px;--headlineFontSizeTablet:36px;--headlineFontSizeMobile:24px;--headlineLineHeight:45px;--headlineLineHeightTablet:45px;--headlineLineHeightMobile:30px\" class=\"hero-title fontWeightRegular\"><strong>Did you know M-M-R\u00ae<sub>II<\/sub> (Measles, Mumps, and Rubella Virus Vaccine Live) is also for adults?<sup>1<\/sup><\/strong><\/h1><p class=\"hero-description\"><\/p><div class=\"hero-btn-group\"><\/div><div class=\"hero-caption\"><\/div><\/div><\/div><\/div><div class=\"hero-caption-2desktop\"><\/div><\/div>\n\n\n<link rel='stylesheet' id='vivid360-spacer-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/spacer\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div style=\"background-color:transparent;--desktop-spacer:8px;--tablet-spacer:8px;--mobile-spacer:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n<link rel='stylesheet' id='vivid360-heading-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/heading\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"afcb81d92-1680-4e34-ae4e-5c0d3e996b83\"><h2 class=\"has-primary-dark-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h2FontSizeDesktop);--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:var(--h2FontSizeMobile);--desktopLineHeightSize:var(--h2LineHeightDesktop);--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>Choose M-M-R<sup>\u00ae<\/sup><sub>II<\/sub> for your adult patients<\/strong><\/h2><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"paragraph-wrapper\"><div class=\"_1374fa56-f338-4e7c-8640-d3cfe1681162 \" id=\"\"><p style=\"font-size:18px\"><strong><em>PRIORIX<\/em> IMMUNE RESPONSE: STUDY 4: Immune responses to <em>PRIORIX<\/em> as a second  dose compared with M-M-R<sup>\u00ae<\/sup><sub>II<\/sub> in participants 7 years of age and older (ATP population)<sup>2,3<\/sup><\/strong><\/p><\/div><\/div>\n\n\n<link rel='stylesheet' id='vivid360-image-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/image\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"650\" height=\"404\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/CAT_MMR_Priorix-Immune-Response_Study4_MAX_v1.svg\" alt=\"\" class=\"wp-image-1300  style-noshadow   \" title=\"\" style=\"height:405px;width:650px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/\/2025\/12\/CAT_MMR_Priorix-Immune-Response_Study4_MAX_v1.svg 650w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/\/2025\/12\/CAT_MMR_Priorix-Immune-Response_Study4_MAX_v1.svg?resize=300,186 300w\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/CAT_MMR_Priorix-Immune-Response_Study4_MAX_v1.svg\" alt=\"\" class=\"wp-image-1300  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" width=\"650\" height=\"500\" title=\"\" style=\"height:500px;width:650px\"\/><\/figure><\/div><\/div>\n\n\n\n<p><strong>Study results:<\/strong><\/p>\n\n\n\n<p><em>PRIORIX<\/em><sup>a<\/sup> was non-inferior compared with <span class=\"no-wrap-text\">M-M-R<sup>\u00ae<\/sup><sub>II<\/sub><\/span> in terms of SRR and antibody GMC to measles (SRR M-M-R<sup>\u00ae<\/sup><sub>II<\/sub> 99% vs <em>PRIORIX<\/em> 99%; GMC (mIU\/mL)<span class=\"no-wrap-text\"> M-M-R<sup>\u00ae<\/sup><sub>II<\/sub><\/span> 1,783 vs <em>PRIORIX<\/em> 1,754; GMC Ratio <em>PRIORIX<\/em>\/M-M-R<sup>\u00ae<\/sup><sub>II<\/sub>, 0.98; 95% CI, 0.89, 1.09), mumps (SRR M-M-R<sup>\u00ae<\/sup><sub>II<\/sub> 100% vs <em>PRIORIX<\/em> 98%; GMC (ELU\/mL) <span class=\"no-wrap-text\">M-M-R<sup>\u00ae<\/sup><sub>II<\/sub><\/span> 110 vs <em>PRIORIX<\/em> 114; GMC Ratio <em>PRIORIX<\/em>\/M-M-R<sup>\u00ae<\/sup><sub>II<\/sub>, 1.04; 95% CI, 0.94, 1.15), and rubella (SRR M-M-R<sup>\u00ae<\/sup><sub>II<\/sub> 100% vs <em>PRIORIX<\/em> 100%; GMC (IU\/mL) <span class=\"no-wrap-text\">M-M-R<sup>\u00ae<\/sup><sub>II<\/sub><\/span> 74 vs <em>PRIORIX<\/em> 76; GMC Ratio <em>PRIORIX<\/em>\/M-M-R<sup>\u00ae<\/sup><sub>II<\/sub>, 1.03; 95% CI, 0.94, 1.12).<sup>2,3<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<p><strong>Study design:<\/strong><br>Randomized, observer-blind, controlled study, conducted in the US, Slovakia, and Estonia, 860 participants 7 years of age and older (median age, 26 years; 7-59 years) received <em>PRIORIX<\/em> (n=426) or <span class=\"no-wrap-text\">M-M-R<sup>\u00ae<\/sup><sub>II<\/sub><\/span> (n=434) as a second dose following previous administration of a combined MMR-containing vaccine. Antibody responses to measles, mumps, and rubella were measured 42 days following the second dose of either vaccine.<sup>2,3,b<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<p><sup>a<\/sup><em>PRIORIX<\/em> (Measles, Mumps, and Rubella Vaccine, Live) is a registered trademark of GSK.<br><sup>b<\/sup>Source: <em>PRIORIX<\/em> Prescribing Information.<br>Brands mentioned are trademarks of their respective owners.<br>ATP, according-to-protocol; GMC, geometric mean concentration; SRR, seroresponse rate.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<div class=\"wp-block-vivid360-image img-container mr-0 ml-0\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/MMRII_Diverse-Group-of-Adults_WebBanner_HI.png?w=1024\" alt=\"\" class=\"wp-image-1303  style-noshadow   \" width=\"1128\" height=\"400\" title=\"\" style=\"height:400px;width:1128px\"\/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/MMRII_Diverse-Group-of-Adults_WebBanner_HI.png\" alt=\"\" class=\"wp-image-1303  style-noshadow mobile-image   \" width=\"3600\" height=\"130\" title=\"\" style=\"height:130px;width:3600px\"\/><div align=\"right\" class=\"capoverlay-container mr-0 ml-0\"><div class=\"overlay-scheme-light overlay-enabled\" align=\"right\">Actor Portrayal<\/div><\/div><\/figure><\/div>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<div class=\"vivid360-heading\" id=\"a9a761809-8369-4a3f-983f-8ae0efd6a93c\"><h2 class=\"content-width fontWeightRegular\" style=\"--desktopFontSize:18px;--tabletFontSize:18px;--mobileFontSize:16px;--desktopLineHeightSize:27px;--tabletLineHeightSize:27px;--mobileLineHeightSize:\" id=\"\"><strong>References<\/strong><\/h2><\/div>\n\n\n<link rel='stylesheet' id='vivid360-list-parent-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/list-parent\/css\/style.css?ver=1766071753' media='all' \/>\n\n<div class=\"vivid-block-list2 content-width isBold \">\n<ol start=\"1\" style=\"--listBulletColor:#333\" class=\"list-bullet-color\">\n<li>Centers for Disease Control and Prevention. Measles Vaccination. Updated January 17, 2025. Accessed October 22, 2025. <span class=\"word-break\">https:\/\/www.cdc.gov\/measles\/<span class=\"no-wrap-text\">vaccines<\/span>\/<span class=\"no-wrap-text\">index.html<\/span><\/span><\/li>\n\n\n\n<li><em>PRIORIX<\/em>. Prescribing Information. GSK; 2024.<\/li>\n\n\n\n<li>Abu-Elyazeed R, Jennings W, Severance R, Noss M, Caplanusi A, Povey M, Henry O. (2018). Immunogenicity and safety of a second dose of a measles-mumps-rubella vaccine administered to healthy participants 7 years of age or older: A phase III, randomized study. <em>Hum Vaccin Immunother<\/em>. 2018; 14(11), 2624\u20132631. <span class=\"word-break\">https:\/\/doi.org\/10.1080\/21645515.2018.1489186<\/span><\/li>\n<\/ol>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>PRIORIX IMMUNE RESPONSE: STUDY 4: Immune responses to PRIORIX as a second dose compared with M-M-R\u00aeII in participants 7 years of age&#8230;<\/p>\n","protected":false},"author":5494,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[],"ga4_page_businessunit":[],"ga4_page_campaign":[],"ga4_page_content_purpose":[],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[],"ga4_page_product":[],"ga4_page_region":[],"ga4_page_therapeuticarea":[],"class_list":["post-1298","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Adult Immune Responses for MMR Vaccines<\/title>\n<meta name=\"description\" content=\"View adult immune response rates and clinical study results for MMR Vaccines.\" 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