{"id":41,"date":"2024-02-29T15:03:15","date_gmt":"2024-02-29T15:03:15","guid":{"rendered":"https:\/\/www.merckvaccines.com\/mmr\/?page_id=41"},"modified":"2026-01-08T06:32:43","modified_gmt":"2026-01-08T06:32:43","slug":"reconstitution","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/mmr\/reconstitution\/","title":{"rendered":"Reconstitution"},"content":{"rendered":"<link rel='stylesheet' id='vivid360-hero-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/hero\/css\/style.min.css?ver=1764613072' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-hero\"><div class=\"vivid360-hero-container align-left align-middle ratio-70-30 horizontal desktop text-align-left has-primary-dark-color is-default-style mobile-is-overlay-style mobile-is-full-overlay mobile-is-opaque-overlay mobile-uses-custom-styles\" style=\"border-width:0;border-style:solid;border-top-left-radius:0;border-top-right-radius:0;border-bottom-right-radius:0;border-bottom-left-radius:0;--minHeight:276px\"><div class=\"wide_screens hidden\" data-value=\"default\"><\/div><picture><source media=\"(max-width: 767px)\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/test_v2.png?w=767\"\/><source media=\"(min-width: 768px) and (max-width:1024px)\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/4.0-Reconstitute_MMRII_Banner_1128px_v2@2x.png?w=1024\"\/><source media=\"(min-width: 1025px) and (max-width:1440px)\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/4.0-Reconstitute_MMRII_Banner_1128px_v2@2x.png?w=1440\"\/><img decoding=\"async\" width=\"2257\" height=\"486\" loading=\"lazy\" data-src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/4.0-Reconstitute_MMRII_Banner_1128px_v2@2x.png?w=1488\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/4.0-Reconstitute_MMRII_Banner_1128px_v2@2x.png?w=1488\" alt=\"\" class=\"hero-image\" style=\"--desktop-focal-x:90%;--desktop-focal-y:26%;--mobile-focal-x:0%;--mobile-focal-y:100%;--tablet-focal-x:90%;--tablet-focal-y:26%\"\/><div class=\"capoverlay-container-desktop right-bottom show custom_margin hide_mobile isMobileOverlayChecked label\" style=\"--top-margin:;--bottom-margin:8px;--left-margin:;--right-margin:16px\"><div class=\"overlay-caption-schema\">Actor Portrayal<\/div><\/div><\/picture><div class=\"hero-wrapper\"><div class=\"hero-content\"><h1 style=\"--headlineFontSize:36px;--headlineFontSizeTablet:36px;--headlineFontSizeMobile:24px;--headlineLineHeight:45px;--headlineLineHeightTablet:45px;--headlineLineHeightMobile:30px\" class=\"hero-title fontWeightRegular\"><strong>Reconstitute M-M-R<sup>\u00ae<\/sup><sub>II<\/sub> (Measles, Mumps, and Rubella Virus Vaccine Live) using a pre-filled diluent syringe<\/strong><\/h1><p class=\"hero-description\"><\/p><div class=\"hero-btn-group\"><\/div><div class=\"hero-caption\"><\/div><\/div><\/div><\/div><div class=\"hero-caption-2desktop\"><\/div><\/div>\n\n\n<link rel='stylesheet' id='vivid360-spacer-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/spacer\/css\/style.min.css?ver=1764613072' media='all' \/>\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<div class=\"wp-block-columns mb-0 is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:75%\"><link rel='stylesheet' id='vivid360-video-module-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/video-module\/css\/style.min.css?ver=1765898918' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-video-module vivid360-block-video-module video-module-center full-page-width\"><div class=\"video-wrapper\"><div data-tracking-video=\"6339780788112\" class=\"vivid360-block-video-module-video-content\"><div><video id=\"video-block\" data-design-category=\"Video\" data-account=\"1905768940001\" data-player=\"default\" data-embed=\"default\" controls data-video-id=\"6339780788112\" data-playlist-id=\"\" data-application-id=\"\" class=\"vjs-fluid video-js\" data-jobcode=\"US-MMR-00343\" aria-labelledby=\"video_label\" aria-describedby=\"video_description\"><\/video><\/div><\/div><div id=\"video_label\" hidden>BrightCove Video<\/div><div id=\"video_description\" aria-live=\"polite\" role=\"caption\" hidden><\/div><figure class=\"text-align-left\"><figcaption><\/figcaption><\/figure><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:0px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<p><strong>Attach a needle to the pre-filled syringe.<\/strong><\/p>\n\n\n<link rel='stylesheet' id='vivid360-image-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/image\/css\/style.min.css?ver=1776695804' media='all' \/>\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"418\" height=\"252\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_1_Figure_v3_LO.png?w=418\" alt=\"\" class=\"wp-image-933  style-noshadow   \" title=\"\" style=\"height:252px;width:418px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_1_Figure_v3_LO.png 418w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_1_Figure_v3_LO.png?resize=300,181 300w\" sizes=\"auto, (max-width: 418px) 100vw, 418px\" \/><img loading=\"lazy\" decoding=\"async\" width=\"418\" height=\"252\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_1_Figure_v3_LO.png?w=418\" alt=\"\" class=\"wp-image-933  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" title=\"\" style=\"height:252px;width:418px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_1_Figure_v3_LO.png 418w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_1_Figure_v3_LO.png?resize=300,181 300w\" sizes=\"auto, (max-width: 418px) 100vw, 418px\" \/><\/figure><\/div><\/div>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<p>Visually inspect the vaccine for discoloration.&nbsp;<span><strong>Slowly inject the entire volume<\/strong>&nbsp;of sterile diluent prefilled syringe into the lyophilized vaccine vial.&nbsp;<strong>Gently agitate to dissolve completely.<\/strong>&nbsp;Discard if the lyophilized vaccine cannot be dissolved. Do not use the product if particulates are present or if it appears discolored.<\/span><\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p>Before reconstitution, the lyophilized vaccine is a light yellow compact crystalline plug. <span class=\"no-wrap-text\">M-M-R<sup>\u00ae<\/sup><sub>II<\/sub><\/span>, when reconstituted, is a clear yellow liquid.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"308\" height=\"375\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_2_Figure_v3_LO.png?w=308\" alt=\"\" class=\"wp-image-937  style-noshadow   \" title=\"\" style=\"height:375px;width:308px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_2_Figure_v3_LO.png 308w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_2_Figure_v3_LO.png?resize=246,300 246w\" sizes=\"auto, (max-width: 308px) 100vw, 308px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_2_Figure_v3_LO.png?w=308\" alt=\"\" class=\"wp-image-937  style-noshadow mobile-image   \" width=\"231\" height=\"281\" title=\"\" style=\"height:281px;width:231px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_2_Figure_v3_LO.png 308w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2024\/03\/CAT_PFS-Diluent_Step_2_Figure_v3_LO.png?resize=246,300 246w\" sizes=\"auto, (max-width: 231px) 100vw, 231px\" \/><\/figure><\/div><\/div>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<p>Visually inspect the vaccine again for discoloration.&nbsp;<strong>Withdraw and administer the entire volume of the reconstituted vaccine.<\/strong><\/p>\n\n\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"308\" height=\"375\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Needle_Updated.png?w=308\" alt=\"\" class=\"wp-image-1279  style-noshadow   \" title=\"\" style=\"height:375px;width:308px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Needle_Updated.png 308w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/Needle_Updated.png?resize=246,300 246w\" sizes=\"auto, (max-width: 308px) 100vw, 308px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/CAT_PFS-Diluent_Step_3_Figure_v4_LO.webp\" alt=\"\" class=\"wp-image-1280  style-noshadow mobile-image   \" width=\"158\" height=\"280\" title=\"\" style=\"height:280px;width:158px\" srcset=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/CAT_PFS-Diluent_Step_3_Figure_v4_LO.webp 316w, https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/CAT_PFS-Diluent_Step_3_Figure_v4_LO.webp?resize=170,300 170w\" sizes=\"auto, (max-width: 158px) 100vw, 158px\" \/><\/figure><\/div><\/div>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n<link rel='stylesheet' id='vivid360-list-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/list\/css\/style.min.css?ver=1764613072' media='all' \/>\n\n<div class=\"vivid-block-list content-width  default-list block-50133a57-62e6-479c-a33f-18e96cb1a369\" data-image=\"\" data-image-mobile=\"\" data-image-all=\"\" data-image-all-mobile=\"\" data-icon-color=\"#333\" data-text-color=\"#333\" data-client-id=\"block-50133a57-62e6-479c-a33f-18e96cb1a369\"><ul class=\"first-level\"><li>If not used immediately, the reconstituted vaccine may be stored between 36\u00b0F to 46\u00b0F <span class=\"no-wrap-text\">(2\u00b0C to 8\u00b0C)<\/span>, protected from light, for up to 8 hours. Discard reconstituted vaccine if it is not used within 8 hours.<\/li><\/ul><\/div>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-vivid360-button-parent btn-block-container content-width button-justify-center\"><link rel='stylesheet' id='vivid360-button-block-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/button\/css\/style.min.css?ver=1765898918' media='all' \/>\n<link rel='stylesheet' id='vivid360-button-parent-block-css-css' href='https:\/\/www.merckvaccines.com\/mmr\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/button-parent\/css\/style.min.css?ver=6.8.5' media='all' \/>\n\n<div class=\"vivid360-button-block fullWidth-mobile\"><a class=\"btn primary primary-regular\" role=\"button\" style=\"font-size:14px;letter-spacing:0.86px;border-radius:4px;border-style:solid;justify-content:center;text-align:center;width:100%\" href=\"https:\/\/www.merckvaccines.com\/mmr\/wp-content\/uploads\/sites\/155\/2025\/12\/US-MMR-00601_MMRV-Family-Storage-Reconstitution-Leave-Behind_v7_CORAL.pdf\" title=\"Get reconstitution pdf\" target=\"_blank\" rel=\"noopener\" data-design-category=\"button\" data-design-label=\"Get reconstitution pdf\" data-design-module=\"element\" data-event-name=\"element_click\">Get reconstitution pdf<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n<\/div>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Attach a needle to the pre-filled syringe. Visually inspect the vaccine for discoloration.&nbsp;Slowly inject the entire volume&nbsp;of sterile diluent prefilled syringe into&#8230;<\/p>\n","protected":false},"author":446,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[226],"ga4_page_businessunit":[234],"ga4_page_campaign":[],"ga4_page_content_purpose":[247],"ga4_page_customer_journey_stage":[295],"ga4_page_customer_specialty":[340],"ga4_page_experience":[],"ga4_page_indication":[423],"ga4_page_material_intent":[481],"ga4_page_product":[540],"ga4_page_region":[780],"ga4_page_therapeuticarea":[836],"class_list":["post-41","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Reconstitution 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