{"id":124,"date":"2024-07-23T10:52:31","date_gmt":"2024-07-23T10:52:31","guid":{"rendered":"https:\/\/www.merckvaccines.com\/proquad\/?page_id=124"},"modified":"2026-01-08T07:07:12","modified_gmt":"2026-01-08T07:07:12","slug":"efficacy","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/proquad\/efficacy\/","title":{"rendered":"Efficacy \u2013 subcutaneous administration"},"content":{"rendered":"\n\n
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Actor Portrayal<\/div><\/div><\/picture>

Strong immune response rates with ProQuad\u00ae<\/sup><\/strong> (Measles, Mumps, Rubella and Varicella Virus Vaccine Live) as a 2nd<\/sup> MMRV dose in children 4-6 years olda<\/sup><\/strong><\/h1>

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ProQuad as a 2nd MMRV vaccine dose administered subcutaneously showed a similar immune response to M-M-R\u00ae<\/sup>II<\/sub> (Measles, Mumps, and Rubella Virus Vaccine Live) and VARIVAX\u00ae<\/sup> (Varicella Virus Vaccine Live)<\/strong><\/h2><\/div>\n\n\n\n
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\"Graph\"Graph<\/figure><\/div><\/div>\n\n\n\n
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Study design<\/strong><\/h3><\/div>\n\n\n\n
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In a clinical trial, 799 healthy 4- to 6-year-old children who had received a primary vaccination with M-M-R\u00ae<\/sup>II<\/sub><\/span> and VARIVAX at least 1 month prior to study were randomized to receive ProQuad subcutaneously and placebo (n=399), M-M-R\u00ae<\/sup>II<\/sub> and placebo concomitantly at separate injection sites (n=205), or M-M-R\u00ae<\/sup>II<\/sub><\/span> and VARIVAX concomitantly at separate injection sites (n=195).<\/p>\n\n\n\n

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a<\/sup>Formal studies to evaluate the clinical efficacy of ProQuad have not been performed.<\/p>\n\n\n\n

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b<\/sup>Observed 6 weeks following vaccine dose administration.<\/p>\n\n\n\n

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See febrile seizures data<\/strong><\/h2>

See febrile seizures data<\/a><\/p><\/div>

<\/i><\/div><\/div><\/div><\/div>\n<\/div>\n\n\n\n
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In a clinical trial, 799 healthy 4- to 6-year-old children who had received a primary vaccination with M-M-R\u00aeII and VARIVAX at least…<\/p>\n","protected":false},"author":522,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[228],"ga4_page_businessunit":[239],"ga4_page_campaign":[],"ga4_page_content_purpose":[262,1066,1067],"ga4_page_customer_journey_stage":[319],"ga4_page_customer_specialty":[375],"ga4_page_experience":[],"ga4_page_indication":[484],"ga4_page_material_intent":[582],"ga4_page_product":[762],"ga4_page_region":[934],"ga4_page_therapeuticarea":[951],"class_list":["post-124","page","type-page","status-publish"],"yoast_head":"\nSecond Dose With ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)<\/title>\n<meta name=\"description\" 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