{"id":148,"date":"2024-07-23T13:27:28","date_gmt":"2024-07-23T13:27:28","guid":{"rendered":"https:\/\/www.merckvaccines.com\/proquad\/?page_id=148"},"modified":"2026-11-05T14:39:04","modified_gmt":"2026-11-05T14:39:04","slug":"dosing-administration","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/","title":{"rendered":"Dosage and administration overview"},"content":{"rendered":"\n\n
<\/div>\n\n\n\n\n
<\/div>\"\"
Actor Portrayal<\/div><\/div><\/picture>

Dosage and administration for ProQuad\u00ae<\/sup> (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)<\/mark><\/strong><\/h1>

<\/p>

<\/div>
<\/div><\/div><\/div><\/div>
<\/div>
<\/div><\/div>\n\n\n\n
<\/div>\n\n\n\n\n

Dosage<\/strong><\/h2><\/div>\n\n\n\n
<\/div>\n\n\n\n
\n
\n

A single dose of ProQuad is approximately 0.5 mL and is administered intramuscularly or subcutaneously. The first dose is usually administered at 12 to 15 months of age but may be given anytime through 12 years of age. <\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/div>\n\n\n\n

The second dose is usually administered at 4 to 6 years of age. At least 1 month should elapse between a dose of a measles-containing vaccine, such as M-M-R\u00ae<\/sup>II<\/sub> <\/span>(Measles, Mumps, and Rubella Virus Vaccine Live), and a dose of ProQuad. At least 3 months should elapse between a dose of varicella-containing vaccine and ProQuad.<\/p>\n<\/div>\n<\/div>\n\n\n\n

<\/div>\n\n\n\n

Flexible route of administration<\/strong><\/h2><\/div>\n\n\n\n
<\/div>\n\n\n\n\n
\"Intramuscular\"Intramuscular<\/figure><\/div><\/div>\n\n\n\n
<\/div>\n\n\n\n

Not actual administration of ProQuad. For illustration purposes only.<\/p>\n\n\n\n

<\/div>\n\n\n\n

ProQuad can be administered via intramuscular or subcutaneous route, giving health care professionals flexibility to choose the same administration route of other common childhood vaccines.1-4<\/sup><\/span><\/strong><\/p>\n\n\n\n

<\/div>\n\n\n\n

Method of administration<\/strong><\/h2><\/div>\n\n\n\n
<\/div>\n\n\n\n

Inject the vaccine intramuscularly or subcutaneously into the outer aspect of the deltoid region of the upper arm or into the higher anterolateral area of the thigh.<\/p>\n\n\n\n

<\/div>\n\n\n\n

<\/p>\n\n\n\n

\n
\n\n
\"\"\/<\/picture><\/figure><\/div>

See storage and handling<\/strong><\/h2>

<\/a><\/p><\/div>

<\/i><\/div><\/div><\/div><\/div>\n<\/div>\n\n\n\n
\n
\"\"\/<\/picture><\/figure><\/div>

See reconstitution instructions<\/strong><\/strong><\/h2>

<\/a><\/p><\/div>

<\/i><\/div><\/div><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n

References<\/strong><\/h4><\/div>\n\n\n\n\n
\n
    \n
  1. PRIORIX. Prescribing Information. GSK; 2025.<\/li>\n\n\n\n
  2. SPIKEVAX. Prescribing Information. Moderna; 2026.<\/li>\n\n\n\n
  3. NUVAXOVID. Prescribing Information. Sanofi; 2026.<\/li>\n\n\n\n
  4. COMIRNATY. Prescribing Information. Pfizer; 2026.<\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    A single dose of ProQuad is approximately 0.5 mL and is administered intramuscularly or subcutaneously. The first dose is usually administered at…<\/p>\n","protected":false},"author":522,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[228],"ga4_page_businessunit":[239],"ga4_page_campaign":[],"ga4_page_content_purpose":[255],"ga4_page_customer_journey_stage":[320],"ga4_page_customer_specialty":[375],"ga4_page_experience":[],"ga4_page_indication":[484],"ga4_page_material_intent":[582],"ga4_page_product":[762],"ga4_page_region":[934],"ga4_page_therapeuticarea":[951],"class_list":["post-148","page","type-page","status-publish"],"yoast_head":"\nDosage and Administration for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)<\/title>\n<meta name=\"description\" content=\"Find dosage information for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live) and review the method of administration.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dosage and Administration for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)\" \/>\n<meta property=\"og:description\" content=\"Find dosage information for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live) and review the method of administration.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/\" \/>\n<meta property=\"og:site_name\" content=\"proquad-mv\" \/>\n<meta property=\"article:modified_time\" content=\"2026-11-05T14:39:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.merckvaccines.com\/proquad\/wp-content\/uploads\/sites\/174\/2026\/11\/2.0_Dosage_and_Administration_ProQuad_Banner_1128px_v2.svg?w=1232\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Dosage and Administration for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)","description":"Find dosage information for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live) and review the method of administration.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/","og_locale":"en_US","og_type":"article","og_title":"Dosage and Administration for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)","og_description":"Find dosage information for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live) and review the method of administration.","og_url":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/","og_site_name":"proquad-mv","article_modified_time":"2026-11-05T14:39:04+00:00","og_image":[{"url":"https:\/\/www.merckvaccines.com\/proquad\/wp-content\/uploads\/sites\/174\/2026\/11\/2.0_Dosage_and_Administration_ProQuad_Banner_1128px_v2.svg?w=1232","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/","url":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/","name":"Dosage and Administration for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live)","isPartOf":{"@id":"https:\/\/www.merckvaccines.com\/proquad\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/#primaryimage"},"image":{"@id":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/#primaryimage"},"thumbnailUrl":"https:\/\/www.merckvaccines.com\/proquad\/wp-content\/uploads\/sites\/174\/2026\/11\/2.0_Dosage_and_Administration_ProQuad_Banner_1128px_v2.svg?w=1232","datePublished":"2024-07-23T13:27:28+00:00","dateModified":"2026-11-05T14:39:04+00:00","description":"Find dosage information for ProQuad\u00ae (Measles, Mumps, Rubella and Varicella Virus Vaccine Live) and review the method of administration.","breadcrumb":{"@id":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/#primaryimage","url":"https:\/\/www.merckvaccines.com\/proquad\/wp-content\/uploads\/sites\/174\/2026\/11\/2.0_Dosage_and_Administration_ProQuad_Banner_1128px_v2.svg","contentUrl":"https:\/\/www.merckvaccines.com\/proquad\/wp-content\/uploads\/sites\/174\/2026\/11\/2.0_Dosage_and_Administration_ProQuad_Banner_1128px_v2.svg","width":1128,"height":242},{"@type":"BreadcrumbList","@id":"https:\/\/www.merckvaccines.com\/proquad\/dosing-administration\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.merckvaccines.com\/proquad\/"},{"@type":"ListItem","position":2,"name":"Dosage and administration overview"}]},{"@type":"WebSite","@id":"https:\/\/www.merckvaccines.com\/proquad\/#website","url":"https:\/\/www.merckvaccines.com\/proquad\/","name":"proquad-mv","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.merckvaccines.com\/proquad\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"acf":[],"_links":{"self":[{"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/pages\/148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/users\/522"}],"replies":[{"embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/comments?post=148"}],"version-history":[{"count":95,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/pages\/148\/revisions"}],"predecessor-version":[{"id":1995,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/pages\/148\/revisions\/1995"}],"wp:attachment":[{"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/media?parent=148"}],"wp:term":[{"taxonomy":"ga4_page_audience","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_audience?post=148"},{"taxonomy":"ga4_page_birn_id","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_birn_id?post=148"},{"taxonomy":"ga4_page_branding","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_branding?post=148"},{"taxonomy":"ga4_page_businessunit","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_businessunit?post=148"},{"taxonomy":"ga4_page_campaign","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_campaign?post=148"},{"taxonomy":"ga4_page_content_purpose","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_content_purpose?post=148"},{"taxonomy":"ga4_page_customer_journey_stage","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_customer_journey_stage?post=148"},{"taxonomy":"ga4_page_customer_specialty","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_customer_specialty?post=148"},{"taxonomy":"ga4_page_experience","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_experience?post=148"},{"taxonomy":"ga4_page_indication","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_indication?post=148"},{"taxonomy":"ga4_page_material_intent","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_material_intent?post=148"},{"taxonomy":"ga4_page_product","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_product?post=148"},{"taxonomy":"ga4_page_region","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_region?post=148"},{"taxonomy":"ga4_page_therapeuticarea","embeddable":true,"href":"https:\/\/www.merckvaccines.com\/proquad\/wp-json\/wp\/v2\/ga4_page_therapeuticarea?post=148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}