{"id":189,"date":"2023-05-15T11:08:33","date_gmt":"2023-05-15T11:08:33","guid":{"rendered":"https:\/\/www.merckvaccines.com\/recombivax-hb\/?page_id=189"},"modified":"2025-11-25T10:21:12","modified_gmt":"2025-11-25T10:21:12","slug":"pediatric-clinical-data","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/recombivax-hb\/pediatric-clinical-data\/","title":{"rendered":"Pediatric clinical data"},"content":{"rendered":"<link rel='stylesheet' id='vivid360-heading-css-css' href='https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/heading\/css\/style.min.css?ver=1764613072' media='all' \/>\n\n<div class=\"vivid360-heading default-hcp-tablet-fontsize\" id=\"a25fcaa0d-1bf5-4f17-a29d-fde777f23c2e\"><h1 class=\"has-primary-dark-color content-width fontWeightRegular\" style=\"--desktopFontSize:36px;--tabletFontSize:var(--h1FontSizeDesktop);--mobileFontSize:24px;--desktopLineHeightSize:45px;--tabletLineHeightSize:var(--h1LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>Pediatric clinical data for <span class=\"no-wrap-text\">RECOMBIVAX HB<sup>\u00ae<\/sup> <\/span>[Hepatitis B Vaccine (Recombinant)]<\/strong><\/h1><\/div>\n\n\n<link rel='stylesheet' id='vivid360-spacer-css-css' href='https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/spacer\/css\/style.min.css?ver=1764613072' media='all' \/>\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8 spacer-undefined\"><\/div>\n\n\n\n<div class=\"vivid360-heading default-hcp-tablet-fontsize\" id=\"ad2f5fc91-4bea-452e-9167-c7ba6a3ac258\"><h2 class=\"has-primary-dark-color content-width fontWeightRegular\" style=\"--desktopFontSize:24px;--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:20px;--desktopLineHeightSize:36px;--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>In clinical studies involving infants, children, and adolescents, 3 doses of&nbsp;RECOMBIVAX HB&nbsp;have been shown to be highly immunogenic<\/strong><\/h2><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n<link rel='stylesheet' id='vivid360-image-css-css' href='https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/image\/css\/style.min.css?ver=1776695804' media='all' \/>\n\n<div class=\"wp-block-vivid360-image img-container\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/DET_Serprotection_chart_2021-1.svg\" alt=\"Immunogenicity of RECOMBIVAX HB in Pediatric Patients Studied in Clinical Trials\" class=\"wp-image-1505  style-noshadow   \" width=\"750\" height=\"413\" title=\"\" style=\"height:413px;width:750px\" srcset=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/\/2025\/11\/DET_Serprotection_chart_2021-1.svg 750w, https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/\/2025\/11\/DET_Serprotection_chart_2021-1.svg?resize=300,165 300w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/DET_Serprotection_chart_2021-2.svg\" alt=\"Immunogenicity of RECOMBIVAX HB in Pediatric Patients Studied in Clinical Trials\" class=\"wp-image-1506  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" width=\"1\" height=\"1\" title=\"\" style=\"height:1px;width:1px\" srcset=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/\/2025\/11\/DET_Serprotection_chart_2021-2.svg 750w, https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/\/2025\/11\/DET_Serprotection_chart_2021-2.svg?resize=150,150 150w, https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/\/2025\/11\/DET_Serprotection_chart_2021-2.svg?resize=300,165 300w\" sizes=\"auto, (max-width: 1px) 100vw, 1px\" \/><\/figure><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"paragraph-wrapper\"><div class=\"_23372b78-3af3-4aa1-95ec-e221acc7e976 \" id=\"\"><p class=\"has-text-color has-small-font-size\" style=\"color:#333e48\"><sup><strong>a<\/strong><\/sup>Seroprotection is defined by the CDC as an anti-HBs level \u226510 mlU\/mL.<sup>1<\/sup><\/p><\/div><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<p class=\"has-text-color has-small-font-size\" style=\"color:#333e48\">Vaccination with RECOMBIVAX HB may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<p class=\"has-text-color has-small-font-size\" style=\"color:#333e48\">The total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unknown at present.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"paragraph-wrapper\"><div class=\"_fdde8a9a-e986-4e0e-ad7a-505faec86101 \" id=\"\"><p class=\"has-text-color has-small-font-size\" style=\"color:#333e48\">CDC, Centers for Disease Control and Prevention; anti-HBs, antibody to hepatitis B surface antigen.<\/p><\/div><\/div>\n\n\n\n<div class=\"vivid360-heading\" id=\"ad11595ee-5ae9-409b-8736-fbe13860126d\"><h2 class=\"content-width fontWeightRegular\" style=\"--desktopFontSize:18px;--tabletFontSize:18px;--mobileFontSize:16px;--desktopLineHeightSize:27px;--tabletLineHeightSize:27px;--mobileLineHeightSize:\" id=\"\"><strong>Reference<\/strong><\/h2><\/div>\n\n\n<link rel='stylesheet' id='vivid360-list-css-css' href='https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/list\/css\/style.min.css?ver=1764613072' media='all' \/>\n\n<div class=\"vivid-block-list content-width  block-aac16b1d-0edf-41bb-bee6-340ca75e1d0e\" data-image=\"\" data-image-mobile=\"\" data-image-all=\"\" data-image-all-mobile=\"\" data-icon-color=\"#333\" data-text-color=\"#333\" data-client-id=\"block-aac16b1d-0edf-41bb-bee6-340ca75e1d0e\"><ol start=\"1\" class=\"first-level default-order\"><li><mark style=\"background-color:rgba(0, 0, 0, 0);color:#333e48\" class=\"has-inline-color\">Mast EE, Weinbaum CM, Fiore AE, et al. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults. <em>MMWR Recomm Rep.<\/em> 2006;55(RR-16):1-CE4.<\/mark><\/li><\/ol><\/div>\n","protected":false},"excerpt":{"rendered":"<p>aSeroprotection is defined by the CDC as an anti-HBs level \u226510 mlU\/mL.1 Vaccination with RECOMBIVAX HB may not result in a protective&#8230;<\/p>\n","protected":false},"author":701,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[227],"ga4_page_businessunit":[235],"ga4_page_campaign":[],"ga4_page_content_purpose":[254],"ga4_page_customer_journey_stage":[298],"ga4_page_customer_specialty":[370],"ga4_page_experience":[],"ga4_page_indication":[466],"ga4_page_material_intent":[570],"ga4_page_product":[633],"ga4_page_region":[942],"ga4_page_therapeuticarea":[961],"class_list":["post-189","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pediatric Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]<\/title>\n<meta name=\"description\" content=\"View 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