Adult\/Dialysis clinical data for RECOMBIVAX HB\u00ae<\/sup><\/span> [Hepatitis B Vaccine (Recombinant)]<\/strong><\/h1><\/div>\n\n\n\n\n<\/div>\n\n\n\n<\/div>\n\n\n\nIn clinical trials, adult and dialysis formulations of RECOMBIVAX HB<\/span> were highly immunogenic<\/strong><\/h2><\/div>\n\n\n\n<\/div>\n\n\n\nImmunogenicity in adults<\/strong><\/h3><\/div>\n\n\n\n<\/div>\n\n\n\nIn healthy adultsa<\/sup> \u2265 20 years of age after the recommended 3-dose series in clinical trials<\/p>\n\n\n\n<\/div>\n\n\n\n\n\n\n![\"Immunogenicity](\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg\" "\\"\\"")
<\/figure><\/div>\n<\/div>\n\n\n\n\nSeroprotection ratesb<\/sup> in healthy adults after the recommended 3-dose series of 10 mcg\/1.0 mL administered at 0, 1, and 6 months, as demonstrated in clinical studies.<\/p>\n\n\n\n<\/div>\n\n\n\nAdapted from West, 1989.1<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\na<\/sup>Dialysis and predialysis patients should receive dialysis formulation (40 mcg\/1.0 mL).<\/p>\n\n\n\n<\/div>\n\n\n\nb<\/sup>Seroprotection is defined by the Centers for Disease Control and Prevention (CDC) as an antibody to hepatitis B surface antigen (anti-HBs) level \u2265 10 mIU\/mL.2<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\nVaccination with RECOMBIVAX HB<\/span> may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n<\/div>\n\n\n\nThe total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unkown at present.<\/p>\n<\/div>\n<\/div>\n\n\n\n
Immunogenicity in predialysis and dialysis patients<\/strong><\/h3><\/div>\n\n\n\n<\/div>\n\n\n\nIn clinical studies (n=28\u201344), RECOMBIVAX HB provided seroprotectiona<\/sup> in 86% of adult predialysis and dialysis patients after the recommended 3-dose series of 40 mcg\/1.0 mL at 0, 1, and 6 months<\/strong> administered in the deltoid muscle<\/strong>1<\/sup><\/h4><\/div>\n\n\n\n<\/div>\n\n\n\n![\"Immunogenicity](\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/DET_DialysisImmunoGenecity_chart_2021-1.svg\" "\\"\\"")
![\"Immunogenicity](\"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/DET_DialysisImmunoGenecity_chart_2021.svg\" "\\"\\"")
<\/figure><\/div>\n\n\n\nAdapted from West, 1989 1<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\na<\/sup>Seroprotection is defined by the CDC as an anti-HBs level \u2265 10 mlU\/mL.2<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\nVaccination with RECOMBIVAX HB may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n
<\/div>\n\n\n\nThe total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unknown at present.<\/p>\n\n\n\n
<\/div>\n\n\n\nAdult and dialysis formulation dosing<\/strong><\/h2><\/div>\n\n\n\n<\/div>\n\n\n\nDosing schedule for RECOMBIVAX HB<\/strong><\/h4><\/div>\n\n\n\n\n\nGroup<\/th> Dose<\/th> Schedule<\/th> Injections<\/th><\/tr><\/thead> Adults \u2265 20 years of age<\/td> 10 mcg (1.0 mL)<\/td> 0, 1, 6 months<\/td> 3<\/td><\/tr> Predialysis and dialysis patients<\/td> 40 mcg (1.0 mL)a<\/sup><\/td>0, 1, 6 months<\/td> 3<\/td><\/tr><\/tbody><\/table><\/small><\/div><\/figure>\n\n\n\n<\/div>\n\n\n\na<\/sup>RECOMBIVAX HB Dialysis Formulation is available in 1-mL (40 mcg\/1.0 mL) single-dose vials.<\/p>\n\n\n\n<\/div>\n\n\n\nReferences<\/strong><\/h2><\/div>\n\n\n\n\n- West DJ. Clinical experience with hepatitis B vaccines. Am J Infect Control<\/em>. 1989;17(3):172\u2013180.<\/li>
- Mast EE, Weinbaum CM, Fiore AE, et al. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults. MMWR Recomm Rep.<\/em> 2006;55(RR-16):1-CE4.<\/li><\/ol><\/div>\n","protected":false},"excerpt":{"rendered":"
In healthy adultsa \u2265 20 years of age after the recommended 3-dose series in clinical trials Seroprotection ratesb in healthy adults after the recommended…<\/p>\n","protected":false},"author":666,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[227],"ga4_page_businessunit":[235],"ga4_page_campaign":[],"ga4_page_content_purpose":[254],"ga4_page_customer_journey_stage":[298],"ga4_page_customer_specialty":[370],"ga4_page_experience":[],"ga4_page_indication":[466],"ga4_page_material_intent":[570],"ga4_page_product":[633],"ga4_page_region":[942],"ga4_page_therapeuticarea":[961],"class_list":["post-528","page","type-page","status-publish"],"yoast_head":"\n
Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]<\/title>\n<meta name=\"description\" content=\"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]\" \/>\n<meta property=\"og:description\" content=\"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.\" \/>\n<meta property=\"og:url\" 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dosing.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/","og_locale":"en_US","og_type":"article","og_title":"Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]","og_description":"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.","og_url":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/","og_site_name":"recombivax-mv","article_modified_time":"2025-11-25T10:37:31+00:00","og_image":[{"url":"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 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information on immunogenicity and formulation dosing.","breadcrumb":{"@id":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/#primaryimage","url":"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg","contentUrl":"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg","width":280,"height":138,"caption":"Immunogenicity of RECOMBIVAX HB in Adults After the Recommended Dose 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In clinical trials, adult and dialysis formulations of RECOMBIVAX HB<\/span> were highly immunogenic<\/strong><\/h2><\/div>\n\n\n\n<\/div>\n\n\n\nImmunogenicity in adults<\/strong><\/h3><\/div>\n\n\n\n<\/div>\n\n\n\nIn healthy adultsa<\/sup> \u2265 20 years of age after the recommended 3-dose series in clinical trials<\/p>\n\n\n\n<\/div>\n\n\n\n\n\n\n<\/figure><\/div>\n<\/div>\n\n\n\n\nSeroprotection ratesb<\/sup> in healthy adults after the recommended 3-dose series of 10 mcg\/1.0 mL administered at 0, 1, and 6 months, as demonstrated in clinical studies.<\/p>\n\n\n\n<\/div>\n\n\n\nAdapted from West, 1989.1<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\na<\/sup>Dialysis and predialysis patients should receive dialysis formulation (40 mcg\/1.0 mL).<\/p>\n\n\n\n<\/div>\n\n\n\nb<\/sup>Seroprotection is defined by the Centers for Disease Control and Prevention (CDC) as an antibody to hepatitis B surface antigen (anti-HBs) level \u2265 10 mIU\/mL.2<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\nVaccination with RECOMBIVAX HB<\/span> may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n<\/div>\n\n\n\nThe total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unkown at present.<\/p>\n<\/div>\n<\/div>\n\n\n\n
Immunogenicity in predialysis and dialysis patients<\/strong><\/h3><\/div>\n\n\n\n<\/div>\n\n\n\nIn clinical studies (n=28\u201344), RECOMBIVAX HB provided seroprotectiona<\/sup> in 86% of adult predialysis and dialysis patients after the recommended 3-dose series of 40 mcg\/1.0 mL at 0, 1, and 6 months<\/strong> administered in the deltoid muscle<\/strong>1<\/sup><\/h4><\/div>\n\n\n\n<\/div>\n\n\n\n<\/figure><\/div>\n\n\n\nAdapted from West, 1989 1<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\na<\/sup>Seroprotection is defined by the CDC as an anti-HBs level \u2265 10 mlU\/mL.2<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\nVaccination with RECOMBIVAX HB may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n
<\/div>\n\n\n\nThe total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unknown at present.<\/p>\n\n\n\n
<\/div>\n\n\n\nAdult and dialysis formulation dosing<\/strong><\/h2><\/div>\n\n\n\n<\/div>\n\n\n\nDosing schedule for RECOMBIVAX HB<\/strong><\/h4><\/div>\n\n\n\n\n\nGroup<\/th> Dose<\/th> Schedule<\/th> Injections<\/th><\/tr><\/thead> Adults \u2265 20 years of age<\/td> 10 mcg (1.0 mL)<\/td> 0, 1, 6 months<\/td> 3<\/td><\/tr> Predialysis and dialysis patients<\/td> 40 mcg (1.0 mL)a<\/sup><\/td>0, 1, 6 months<\/td> 3<\/td><\/tr><\/tbody><\/table><\/small><\/div><\/figure>\n\n\n\n<\/div>\n\n\n\na<\/sup>RECOMBIVAX HB Dialysis Formulation is available in 1-mL (40 mcg\/1.0 mL) single-dose vials.<\/p>\n\n\n\n<\/div>\n\n\n\nReferences<\/strong><\/h2><\/div>\n\n\n\n\n- West DJ. Clinical experience with hepatitis B vaccines. Am J Infect Control<\/em>. 1989;17(3):172\u2013180.<\/li>
- Mast EE, Weinbaum CM, Fiore AE, et al. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults. MMWR Recomm Rep.<\/em> 2006;55(RR-16):1-CE4.<\/li><\/ol><\/div>\n","protected":false},"excerpt":{"rendered":"
In healthy adultsa \u2265 20 years of age after the recommended 3-dose series in clinical trials Seroprotection ratesb in healthy adults after the recommended…<\/p>\n","protected":false},"author":666,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[227],"ga4_page_businessunit":[235],"ga4_page_campaign":[],"ga4_page_content_purpose":[254],"ga4_page_customer_journey_stage":[298],"ga4_page_customer_specialty":[370],"ga4_page_experience":[],"ga4_page_indication":[466],"ga4_page_material_intent":[570],"ga4_page_product":[633],"ga4_page_region":[942],"ga4_page_therapeuticarea":[961],"class_list":["post-528","page","type-page","status-publish"],"yoast_head":"\n
Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]<\/title>\n<meta name=\"description\" content=\"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]\" \/>\n<meta property=\"og:description\" content=\"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.\" \/>\n<meta property=\"og:url\" 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dosing.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/","og_locale":"en_US","og_type":"article","og_title":"Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]","og_description":"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.","og_url":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/","og_site_name":"recombivax-mv","article_modified_time":"2025-11-25T10:37:31+00:00","og_image":[{"url":"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 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information on immunogenicity and formulation dosing.","breadcrumb":{"@id":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/#primaryimage","url":"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg","contentUrl":"https:\/\/www.merckvaccines.com\/recombivax-hb\/wp-content\/uploads\/sites\/83\/2025\/11\/CAT_RHB_96_graphic_v3.svg","width":280,"height":138,"caption":"Immunogenicity of RECOMBIVAX HB in Adults After the Recommended Dose 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Immunogenicity in adults<\/strong><\/h3><\/div>\n\n\n\n<\/div>\n\n\n\nIn healthy adultsa<\/sup> \u2265 20 years of age after the recommended 3-dose series in clinical trials<\/p>\n\n\n\n<\/div>\n\n\n\n\n\n\n<\/figure><\/div>\n<\/div>\n\n\n\n\nSeroprotection ratesb<\/sup> in healthy adults after the recommended 3-dose series of 10 mcg\/1.0 mL administered at 0, 1, and 6 months, as demonstrated in clinical studies.<\/p>\n\n\n\n<\/div>\n\n\n\nAdapted from West, 1989.1<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\na<\/sup>Dialysis and predialysis patients should receive dialysis formulation (40 mcg\/1.0 mL).<\/p>\n\n\n\n<\/div>\n\n\n\nb<\/sup>Seroprotection is defined by the Centers for Disease Control and Prevention (CDC) as an antibody to hepatitis B surface antigen (anti-HBs) level \u2265 10 mIU\/mL.2<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\nVaccination with RECOMBIVAX HB<\/span> may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n<\/div>\n\n\n\nThe total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unkown at present.<\/p>\n<\/div>\n<\/div>\n\n\n\n
Immunogenicity in predialysis and dialysis patients<\/strong><\/h3><\/div>\n\n\n\n<\/div>\n\n\n\nIn clinical studies (n=28\u201344), RECOMBIVAX HB provided seroprotectiona<\/sup> in 86% of adult predialysis and dialysis patients after the recommended 3-dose series of 40 mcg\/1.0 mL at 0, 1, and 6 months<\/strong> administered in the deltoid muscle<\/strong>1<\/sup><\/h4><\/div>\n\n\n\n<\/div>\n\n\n\n<\/figure><\/div>\n\n\n\nAdapted from West, 1989 1<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\na<\/sup>Seroprotection is defined by the CDC as an anti-HBs level \u2265 10 mlU\/mL.2<\/sup><\/p>\n\n\n\n<\/div>\n\n\n\nVaccination with RECOMBIVAX HB may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n
<\/div>\n\n\n\nThe total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unknown at present.<\/p>\n\n\n\n
<\/div>\n\n\n\nAdult and dialysis formulation dosing<\/strong><\/h2><\/div>\n\n\n\n<\/div>\n\n\n\nDosing schedule for RECOMBIVAX HB<\/strong><\/h4><\/div>\n\n\n\n\n\nGroup<\/th> Dose<\/th> Schedule<\/th> Injections<\/th><\/tr><\/thead> Adults \u2265 20 years of age<\/td> 10 mcg (1.0 mL)<\/td> 0, 1, 6 months<\/td> 3<\/td><\/tr> Predialysis and dialysis patients<\/td> 40 mcg (1.0 mL)a<\/sup><\/td>0, 1, 6 months<\/td> 3<\/td><\/tr><\/tbody><\/table><\/small><\/div><\/figure>\n\n\n\n<\/div>\n\n\n\na<\/sup>RECOMBIVAX HB Dialysis Formulation is available in 1-mL (40 mcg\/1.0 mL) single-dose vials.<\/p>\n\n\n\n<\/div>\n\n\n\nReferences<\/strong><\/h2><\/div>\n\n\n\n\n- West DJ. Clinical experience with hepatitis B vaccines. Am J Infect Control<\/em>. 1989;17(3):172\u2013180.<\/li>
- Mast EE, Weinbaum CM, Fiore AE, et al. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults. MMWR Recomm Rep.<\/em> 2006;55(RR-16):1-CE4.<\/li><\/ol><\/div>\n","protected":false},"excerpt":{"rendered":"
In healthy adultsa \u2265 20 years of age after the recommended 3-dose series in clinical trials Seroprotection ratesb in healthy adults after the recommended…<\/p>\n","protected":false},"author":666,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[227],"ga4_page_businessunit":[235],"ga4_page_campaign":[],"ga4_page_content_purpose":[254],"ga4_page_customer_journey_stage":[298],"ga4_page_customer_specialty":[370],"ga4_page_experience":[],"ga4_page_indication":[466],"ga4_page_material_intent":[570],"ga4_page_product":[633],"ga4_page_region":[942],"ga4_page_therapeuticarea":[961],"class_list":["post-528","page","type-page","status-publish"],"yoast_head":"\n
Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]<\/title>\n<meta name=\"description\" content=\"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.merckvaccines.com\/recombivax-hb\/adult-dialysis-clinical-data\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adult and Dialysis Clinical Data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)]\" \/>\n<meta property=\"og:description\" content=\"View clinical data for RECOMBIVAX HB\u00ae [Hepatitis B Vaccine (Recombinant)], including information on immunogenicity and formulation dosing.\" \/>\n<meta property=\"og:url\" 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In healthy adultsa<\/sup> \u2265 20 years of age after the recommended 3-dose series in clinical trials<\/p>\n\n\n\n Seroprotection ratesb<\/sup> in healthy adults after the recommended 3-dose series of 10 mcg\/1.0 mL administered at 0, 1, and 6 months, as demonstrated in clinical studies.<\/p>\n\n\n\n Adapted from West, 1989.1<\/sup><\/p>\n\n\n\n a<\/sup>Dialysis and predialysis patients should receive dialysis formulation (40 mcg\/1.0 mL).<\/p>\n\n\n\n b<\/sup>Seroprotection is defined by the Centers for Disease Control and Prevention (CDC) as an antibody to hepatitis B surface antigen (anti-HBs) level \u2265 10 mIU\/mL.2<\/sup><\/p>\n\n\n\n Vaccination with RECOMBIVAX HB<\/span> may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n The total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unkown at present.<\/p>\n<\/div>\n<\/div>\n\n\n\n Adapted from West, 1989 1<\/sup><\/p>\n\n\n\n a<\/sup>Seroprotection is defined by the CDC as an anti-HBs level \u2265 10 mlU\/mL.2<\/sup><\/p>\n\n\n\n Vaccination with RECOMBIVAX HB may not result in a protective response in all susceptible vaccinees.<\/p>\n\n\n\n The total duration of the protective effect of RECOMBIVAX HB in healthy vaccinees is unknown at present.<\/p>\n\n\n\n a<\/sup>RECOMBIVAX HB Dialysis Formulation is available in 1-mL (40 mcg\/1.0 mL) single-dose vials.<\/p>\n\n\n\n In healthy adultsa \u2265 20 years of age after the recommended 3-dose series in clinical trials Seroprotection ratesb in healthy adults after the recommended…<\/p>\n","protected":false},"author":666,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[227],"ga4_page_businessunit":[235],"ga4_page_campaign":[],"ga4_page_content_purpose":[254],"ga4_page_customer_journey_stage":[298],"ga4_page_customer_specialty":[370],"ga4_page_experience":[],"ga4_page_indication":[466],"ga4_page_material_intent":[570],"ga4_page_product":[633],"ga4_page_region":[942],"ga4_page_therapeuticarea":[961],"class_list":["post-528","page","type-page","status-publish"],"yoast_head":"\n<\/figure><\/div>\n<\/div>\n\n\n\nImmunogenicity in predialysis and dialysis patients<\/strong><\/h3><\/div>\n\n\n\n
In clinical studies (n=28\u201344), RECOMBIVAX HB provided seroprotectiona<\/sup> in 86% of adult predialysis and dialysis patients after the recommended 3-dose series of 40 mcg\/1.0 mL at 0, 1, and 6 months<\/strong> administered in the deltoid muscle<\/strong>1<\/sup><\/h4><\/div>\n\n\n\n
<\/figure><\/div>\n\n\n\nAdult and dialysis formulation dosing<\/strong><\/h2><\/div>\n\n\n\n
Dosing schedule for RECOMBIVAX HB<\/strong><\/h4><\/div>\n\n\n\n\n\n
Group<\/th> Dose<\/th> Schedule<\/th> Injections<\/th><\/tr><\/thead> Adults \u2265 20 years of age<\/td> 10 mcg (1.0 mL)<\/td> 0, 1, 6 months<\/td> 3<\/td><\/tr> Predialysis and dialysis patients<\/td> 40 mcg (1.0 mL)a<\/sup><\/td> 0, 1, 6 months<\/td> 3<\/td><\/tr><\/tbody><\/table> References<\/strong><\/h2><\/div>\n\n\n\n\n