{"id":848,"date":"2024-06-13T13:33:34","date_gmt":"2024-06-13T13:33:34","guid":{"rendered":"https:\/\/www.merckvaccines.com\/rotateq\/?page_id=848"},"modified":"2026-06-16T16:52:08","modified_gmt":"2026-06-16T16:52:08","slug":"rotavirus-strain-coverage","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/rotateq\/rotavirus-strain-coverage\/","title":{"rendered":"Rotavirus Strain Coverage"},"content":{"rendered":"<link rel='stylesheet' id='vivid360-hero-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/hero\/css\/style.min.css?ver=1779097389' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-hero\"><div class=\"vivid360-hero-container align-left align-middle ratio-70-30 horizontal mobile text-align-left has-white-color is-default-style mobile-uses-desktop-styles\" style=\"border-width:0;border-style:solid;border-top-left-radius:0;border-top-right-radius:0;border-bottom-right-radius:0;border-bottom-left-radius:0;--minHeight:250px;--mobileMinHeight:100px\"><div class=\"wide_screens hidden\" data-value=\"default\"><\/div><picture><source media=\"(max-width: 767px)\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/mobile-banner_new_614a64.png?w=767\"\/><source media=\"(min-width: 768px) and (max-width: 1024px)\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/mobile-banner_new_614a64.png?w=1024\"\/><source media=\"(min-width: 1025px) and (max-width:1440px)\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Rotavirus-Strain-Coverage_banner_1128px_v2.svg?w=1440\"\/><img decoding=\"async\" width=\"1128\" height=\"242\" loading=\"lazy\" data-src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Rotavirus-Strain-Coverage_banner_1128px_v2.svg?w=1232\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Rotavirus-Strain-Coverage_banner_1128px_v2.svg?w=1232\" alt=\"\" class=\"hero-image\" style=\"--desktop-focal-x:100%;--desktop-focal-y:50%;--mobile-focal-x:50%;--mobile-focal-y:50%;--tablet-focal-x:50%;--tablet-focal-y:50%\"\/><\/picture><div class=\"hero-wrapper\"><div class=\"hero-content\"><h1 style=\"--headlineFontSize:36px;--headlineFontSizeTablet:36px;--headlineFontSizeMobile:24px;--headlineLineHeight:45px;--headlineLineHeightTablet:45px;--headlineLineHeightMobile:30px\" class=\"hero-title fontWeightRegular\"><mark style=\"background-color:rgba(0, 0, 0, 0);color:#4f0b7b\" class=\"has-inline-color\"><strong>Is your rotavirus vaccine indicated to help prevent RGE caused by G2?<\/strong><sup>1<\/sup><\/mark><\/h1><p class=\"hero-description\"><\/p><div class=\"hero-btn-group\"><\/div><div class=\"hero-caption\"><\/div><\/div><\/div><\/div><div class=\"hero-caption-2mobile\"><\/div><\/div>\n\n\n<link rel='stylesheet' id='vivid360-spacer-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/spacer\/css\/style.min.css?ver=1764595895' media='all' \/>\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n<link rel='stylesheet' id='vivid360-heading-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/heading\/css\/style.min.css?ver=1764595895' media='all' \/>\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"a0426e522-5b9a-4569-a583-66b8dc5c0c81\"><h2 class=\"has-primary-color has-text-align-left content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h2FontSizeDesktop);--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:var(--h2FontSizeMobile);--desktopLineHeightSize:var(--h2LineHeightDesktop);--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:;--tabletAlign:left;--mobileAlign:left\" id=\"\"><strong>RotaTeq is the only rotavirus vaccine indicated to help protect against RGE caused by 5 strains, including G2<\/strong><sup>1<\/sup><\/h2><\/div>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:49%\"><link rel='stylesheet' id='vivid360-image-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/image\/css\/style.min.css?ver=1778513879' media='all' \/>\n\n<div class=\"wp-block-vivid360-image img-container mt-0 ml-0 mb-0 mr-0\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png\" alt=\"\" class=\"wp-image-2552  style-noshadow   \" width=\"400\" height=\"142\" title=\"RotaTeq-v-Rotarix_Including-G2_VISUAL@2x\" style=\"height:142px;width:400px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png 794w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png?resize=300,106 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png?resize=768,272 768w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png\" alt=\"\" class=\"wp-image-2552  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" width=\"794\" height=\"281\" title=\"RotaTeq-v-Rotarix_Including-G2_VISUAL@2x\" style=\"height:281px;width:794px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png 794w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png?resize=300,106 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png?resize=768,272 768w\" sizes=\"auto, (max-width: 794px) 100vw, 794px\" \/><\/figure><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<p>RotaTeq is indicated for the prevention of rotavirus gastroenteritis in infants and children caused by Types G1, G2, G3, G4, and G9 when administered as a 3-dose series to infants between the ages of 6 to 32 weeks. The first dose of RotaTeq should be administered between 6 and 12 weeks of age.<\/p>\n\n\n\n<p><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:2%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:49%\">\n<div class=\"wp-block-vivid360-image img-container mt-0 ml-0 mb-0 mr-0\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/ROTARIX_RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png\" alt=\"\" class=\"wp-image-2553  style-noshadow   \" width=\"333\" height=\"142\" title=\"ROTARIX_RotaTeq-v-Rotarix_Including-G2_VISUAL@2x\" style=\"height:142px;width:333px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/ROTARIX_RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png 696w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/ROTARIX_RotaTeq-v-Rotarix_Including-G2_VISUAL@2x.png?resize=300,128 300w\" sizes=\"auto, (max-width: 333px) 100vw, 333px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Asset-1@2x-2.png\" alt=\"\" class=\"wp-image-2584  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" width=\"1561\" height=\"603\" title=\"Asset-1@2x-2\" style=\"height:603px;width:1561px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Asset-1@2x-2.png 1561w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Asset-1@2x-2.png?resize=300,116 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Asset-1@2x-2.png?resize=768,297 768w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Asset-1@2x-2.png?resize=1024,396 1024w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Asset-1@2x-2.png?resize=1536,593 1536w\" sizes=\"auto, (max-width: 1561px) 100vw, 1561px\" \/><\/figure><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<p><em>Rotarix<\/em> is indicated for the prevention of rotavirus gastroenteritis caused by G1 and non-G1 types (G3, G4, and G9) when administered as a 2-dose series. <em>Rotarix<\/em> is approved for use in infants 6 weeks and up to 24 weeks of age.<sup>1<\/sup><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"a7cbab937-e685-4e42-b87b-fe0f493de208\"><h2 class=\"has-primary-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h2FontSizeDesktop);--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:var(--h2FontSizeMobile);--desktopLineHeightSize:var(--h2LineHeightDesktop);--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>G2 type &#8211; genetically distinct from other common rotavirus types.<\/strong><sup>2,3<\/sup><\/h2><\/div>\n\n\n\n<p>These 5 common rotavirus strains belong to 2 distinct, minimally related genogroups.<sup>2,3<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n\n<div class=\"wp-block-columns mb-0 is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<p class=\"has-text-align-center\"><strong>Wa GENOGROUP<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><mark style=\"background-color:rgba(0, 0, 0, 0);color:#00a7a5\" class=\"has-inline-color\"><strong>G1P[8]<\/strong><\/mark> , <mark style=\"background-color:rgba(0, 0, 0, 0);color:#54b748\" class=\"has-inline-color\"><strong>G3P[8]<\/strong><\/mark> ,<mark style=\"background-color:rgba(0, 0, 0, 0);color:#8bc43f\" class=\"has-inline-color\"><strong>G4P[8]<\/strong><\/mark>, <mark style=\"background-color:rgba(0, 0, 0, 0);color:#828685\" class=\"has-inline-color\"><strong>G9[8]<\/strong><\/mark><\/p>\n<\/div>\n\n\n\n<div class=\"column-wrapper _1ae104bd-d9fb-4dde-8e26-4fa7aa53718c\"><style>\n\t\t\t\t@media (min-width: 1024px) {\n\t\t\t\t\t.column-wrapper {\n\t\t\t\t\t\tdisplay: contents;\n\t\t\t\t\t}\n\t\t\t\t}\n\t\t\t\t@media (max-width: 1024px) {\n\t\t\t\t\t#block-1ae104bd-d9fb-4dde-8e26-4fa7aa53718c,\n\t\t\t\t\t._1ae104bd-d9fb-4dde-8e26-4fa7aa53718c {\n\t\t\t\t\t\tdisplay: contents;\n\t\t\t\t\t\t\n\t\t\t\t\t}\n\t\t\t\t\t.wp-block-columns:not(.is-not-stacked-on-mobile)>.column-wrapper {\n\t\t\t\t\t\tflex-basis: 100% !important;\n\t\t\t\t\t}\n\t\t\t\t\t.column-wrapper .wp-block-column {\n\t\t\t\t\t\torder: inherit;\n\t\t\t\t\t}\n\t\t\t\t}\n\t\t\t\t@media (max-width: 767px) {\n\t\t\t\t\t#block-1ae104bd-d9fb-4dde-8e26-4fa7aa53718c,\n\t\t\t\t\t._1ae104bd-d9fb-4dde-8e26-4fa7aa53718c {\n\t\t\t\t\t\tflex-basis: 0% !important;display: unset !important;\n\t\t\t\t\t\t\n\t\t\t\t\t}\n\t\t\t\t\t.column-wrapper .wp-block-column {\n\t\t\t\t\t\torder: inherit;\n\t\t\t\t\t}\n\t\t\t\t}\n\t\t\t\t<\/style><div class=\"wp-block-column is-vertically-aligned-bottom mt-0 ml-0 mb-0 mr-0 is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:5%\">\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Line-5.png\" alt=\"\" class=\"wp-image-2586  style-noshadow   \" width=\"1\" height=\"35\" title=\"Line-5\" style=\"height:35px;width:1px\"\/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/Line-5_new.png\" alt=\"\" class=\"wp-image-2587  style-noshadow mobile-image   \" width=\"140\" height=\"1\" title=\"Line-5_new\" style=\"height:1px;width:140px\"\/><\/figure><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<p class=\"has-text-align-center\"><strong>DS-1 GENOGROUP <\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-light-color\"><strong>G2P[4]<\/strong><\/mark><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:45%\"><\/div>\n<\/div>\n\n\n<link rel='stylesheet' id='vivid360-list-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/list\/css\/style.min.css?ver=1764595895' media='all' \/>\n\n<div class=\"vivid-block-list content-width has-primary-color default-list block-f9c7b222-a194-4ae3-a61e-f0e205efeef7 mt-0\" data-image=\"\" data-image-mobile=\"\" data-image-all=\"\" data-image-all-mobile=\"\" data-icon-color=\"#542d88\" data-text-color=\"#333\" data-client-id=\"block-f9c7b222-a194-4ae3-a61e-f0e205efeef7\"><ul class=\"first-level\"><li>Of these common types, G1, G3, G4, and G9 are typically associated with protein P[8], while G2 is commonly associated with protein P[4].<sup>2,3<\/sup><\/li><li>In other words, G2 strains generally do not share P surface proteins with these other common rotavirus G types.<sup>2,3<\/sup><\/li><\/ul><\/div>\n\n\n\n<div style=\"background-color:transparent;--desktop-spacer:24px;--tablet-spacer:24px;--mobile-spacer:24px\" class=\"wp-block-vivid360-spacer vivid360-spacer-desktop vivid360-spacer-tablet vivid360-spacer-mobile\"><\/div>\n\n\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"ae4b20508-c9f5-4dab-a8e1-15f79e26f455\"><h2 class=\"has-primary-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h2FontSizeDesktop);--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:var(--h2FontSizeMobile);--desktopLineHeightSize:var(--h2LineHeightDesktop);--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>8-year active CDC surveillance study showed rotavirus strains varied from season to season, with G2 present in every year<sup>4<\/sup>:<\/strong><\/h2><\/div>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n\n<div class=\"wp-block-vivid360-image img-container mt-0 ml-0\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"996\" height=\"401\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1-1.png\" alt=\"\" class=\"wp-image-2591  style-noshadow deskHeightAuto deskWidthAuto \" title=\"CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1 (1)\" style=\"height:401px;width:996px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1-1.png 996w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1-1.png?resize=300,121 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1-1.png?resize=768,309 768w\" sizes=\"auto, (max-width: 996px) 100vw, 996px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1.png\" alt=\"\" class=\"wp-image-2554  style-noshadow mobile-image deskHeightAuto deskWidthAuto \" width=\"996\" height=\"401\" title=\"CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1\" style=\"height:undefinedpx;width:undefinedpx\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1.png 996w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1.png?resize=300,121 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/CAT_8-year-active-surveillance-study_GRAPH_MVcom@2x-1.png?resize=768,309 768w\" sizes=\"auto, (max-width: 996px) 100vw, 996px\" \/><\/figure><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p class=\"has-medium-font-size\">Distribution of common genotypes detected among children aged 8 to 59 months by surveillance year, NVSN, 2012 to 2019 (N=1,197)<\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<div class=\"paragraph-wrapper\"><div class=\"_c44237c6-01bb-4fdc-9b77-e2837554f925 \" id=\"\"><p style=\"font-size:16px\"><sup>a<\/sup>None of the current rotavirus vaccines are indicated to cover strain G12.<sup>1<\/sup><\/p><\/div><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<p><strong>Study design:<\/strong><\/p>\n\n\n\n<p>The CDC used a test-negative, case-control design to estimate rotavirus VE against laboratory-confirmed rotavirus infections among children aged 8 months and older (N=16,188) who visited the ED or were admitted to the hospital at 8 US NVSN sites from 2009\u20132022 (equivalent to calendar year end 2010 to 2022). Across the 13 surveillance years, the study examined rotavirus case prevalence, vaccine coverage, and calculated VE at preventing rotavirus-associated ED visits or hospitalizations. All analyses were restricted to children 8 months to 4 years, except for the age-stratified VE estimates, which included children 8 months to 17 years. Rotavirus genotype data from 2012\u20132019 were analyzed for children 8 months to 59 months (N=1,197).<sup>4<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<p>CDC, Centers for Disease Control and Prevention; ED, emergency department; NVSN, New Vaccine Surveillance Network; RGE, rotavirus gastroenteritis; VE, vaccine effectiveness.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"a1ca5d442-99f9-48cf-a322-48e0bc7ab103\"><h2 class=\"has-primary-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h2FontSizeDesktop);--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:var(--h2FontSizeMobile);--desktopLineHeightSize:var(--h2LineHeightDesktop);--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>From 2012\u20132019, G2 was the second most commonly reported of 4 vaccine-covered strains (G1, G2, G3, and G9)<\/strong><sup>1,4,a,b<\/sup><\/h2><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"paragraph-wrapper\"><div class=\"_4979c867-ad73-4ade-bf10-1bc93d794429 \" id=\"\"><p class=\"has-large-font-size\"><strong>Among vaccine-covered strains<\/strong><sup>a<\/sup><strong>&nbsp;(n=303\/N=1,197, 25.3% of all reported strains) in specific patient populations<\/strong><sup>1,4<\/sup><\/p><\/div><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:48%\">\n<div class=\"vivid360-heading\" id=\"ab7b02877-a28c-4097-a07c-7e7baff1c974\"><h3 class=\"has-primary-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h3FontSizeDesktop);--tabletFontSize:var(--h3FontSizeDesktop);--mobileFontSize:var(--h3FontSizeMobile);--desktopLineHeightSize:var(--h3LineHeightDesktop);--tabletLineHeightSize:var(--h3LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>G2 was the most common strain in<\/strong><sup>4,c<\/sup><strong>:<\/strong><\/h3><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<div class=\"wp-block-vivid360-image img-container mt-0 ml-0 mb-0 mr-0\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png\" alt=\"38.8% Black or African American, non-Hispanic, 35.0% Publicly Insured Only, 33.6% Emergency-Department (Non-hospitalized)\" class=\"wp-image-2555  style-noshadow deskHeightAuto  \" width=\"565\" height=\"360\" title=\"G2-was-the-most-common-strain_VISUAL@2x\" style=\"height:360px;width:565px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png 975w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png?resize=300,191 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png?resize=768,489 768w\" sizes=\"auto, (max-width: 565px) 100vw, 565px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png\" alt=\"38.8% Black or African American, non-Hispanic, 35.0% Publicly Insured Only, 33.6% Emergency-Department (Non-hospitalized)\" class=\"wp-image-2555  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" width=\"975\" height=\"621\" title=\"G2-was-the-most-common-strain_VISUAL@2x\" style=\"height:621px;width:975px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png 975w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png?resize=300,191 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-most-common-strain_VISUAL@2x.png?resize=768,489 768w\" sizes=\"auto, (max-width: 975px) 100vw, 975px\" \/><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:4%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:48%\">\n<div class=\"vivid360-heading\" id=\"a0b939057-b237-4672-af3c-e7779d9b832c\"><h3 class=\"has-primary-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h3FontSizeDesktop);--tabletFontSize:var(--h3FontSizeDesktop);--mobileFontSize:var(--h3FontSizeMobile);--desktopLineHeightSize:var(--h3LineHeightDesktop);--tabletLineHeightSize:var(--h3LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>G2 was the second most common strain in<\/strong><sup>4,c<\/sup><strong>:<\/strong><\/h3><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<div class=\"wp-block-vivid360-image img-container mt-0 ml-0 mb-0 mr-0\"><figure class=\"wp-block-vivid360-image is-style-default has-mobile-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png\" alt=\"26.2% White, non-Hispanic, 23.7% Privately Insured Only, 29.0% Hospitalized, 27.0% Hispanic or Latino\" class=\"wp-image-2556  style-noshadow deskHeightAuto  \" width=\"565\" height=\"360\" title=\"G2-was-the-second-most-common-strain_VISUAL@2x\" style=\"height:360px;width:565px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png 975w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png?resize=300,191 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png?resize=768,489 768w\" sizes=\"auto, (max-width: 565px) 100vw, 565px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png\" alt=\"26.2% White, non-Hispanic, 23.7% Privately Insured Only, 29.0% Hospitalized, 27.0% Hispanic or Latino\" class=\"wp-image-2556  style-noshadow mobile-image mobHeightAuto mobWidthAuto \" width=\"975\" height=\"621\" title=\"G2-was-the-second-most-common-strain_VISUAL@2x\" style=\"height:621px;width:975px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png 975w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png?resize=300,191 300w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/G2-was-the-second-most-common-strain_VISUAL@2x.png?resize=768,489 768w\" sizes=\"auto, (max-width: 975px) 100vw, 975px\" \/><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p class=\"has-small-font-size\"><sup>a<\/sup>Vaccine-covered strains include G1, G2, G3, and G9. Prevalence of G4, a vaccine-covered strain, was not specified. None of the current rotavirus vaccines are indicated to cover strain G12.<sup>1,4<\/sup><\/p>\n\n\n\n<p class=\"has-small-font-size\"><sup>b<\/sup>Between 2012\u20132019 and among vaccine-covered strains (N=303), 35.3% (N=107) of cases were attributed to G3, 32.7% (N=99) were attributed to G2, 17.2% (N=52) were attributed to G1, and 14.9% (N=45) were attributed to G9 in children &lt;5 years of age.<sup>1,4<\/sup><\/p>\n\n\n\n<p class=\"has-small-font-size\"><sup>c<\/sup>The prevalence of G2 among vaccine-covered strains (G1, G2, G3, G9) was calculated by dividing the number of G2 cases in specific populations (n) by the total cases for vaccine-covered strains in that population (N).<sup>1,4<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n<link rel='stylesheet' id='vivid360-row-module-css-css' 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https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2024\/06\/CAT_ROT_RotaTeq_Product_Shot_MAX.webp?resize=398,1024 398w\" sizes=\"auto, (max-width: 74px) 100vw, 74px\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2024\/06\/CAT_ROT_RotaTeq_Product_Shot_MAX.webp?w=398\" alt=\"\" class=\"wp-image-507  style-noshadow mobile-image   \" width=\"44\" height=\"113\" title=\"\" style=\"height:113px;width:44px\" srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2024\/06\/CAT_ROT_RotaTeq_Product_Shot_MAX.webp 500w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2024\/06\/CAT_ROT_RotaTeq_Product_Shot_MAX.webp?resize=117,300 117w, https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2024\/06\/CAT_ROT_RotaTeq_Product_Shot_MAX.webp?resize=398,1024 398w\" sizes=\"auto, (max-width: 44px) 100vw, 44px\" \/><figcaption class=\"caption-align-center\">Actual size not shown<\/figcaption><figcaption class=\"caption-align-center mobile-caption\">Actual size not shown<\/figcaption><\/figure><\/div><\/div>\n\n\n\n<div class=\"vivid360-heading\" id=\"a14a70434-7785-45a5-8c2b-68589223f6e7\"><h4 class=\"has-primary-color has-text-align-center content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h4FontSizeDesktop);--tabletFontSize:var(--h4FontSizeDesktop);--mobileFontSize:var(--h4FontSizeMobile);--desktopLineHeightSize:var(--h4LineHeightDesktop);--tabletLineHeightSize:var(--h4LineHeightDesktop);--mobileLineHeightSize:;--tabletAlign:center;--mobileAlign:center\" id=\"\"><strong>Looking to stock RotaTeq in your practice?<\/strong><\/h4><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p class=\"has-text-align-center\">Simply register or log in to your account to get started.<\/p>\n\n\n\n<div 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href=\"https:\/\/ordering.merckvaccines.com\/RotaTeq\/Pages\/home?CategoryDomainName=Merck-Vaccines\" title=\"Order RotaTeq today\" target=\"_blank\" rel=\"noopener\" data-design-category=\"button\" data-design-label=\"Order RotaTeq today\" data-design-module=\"element\" data-event-name=\"element_click\">Order RotaTeq today<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"background-color:transparent;height:32px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-32\"><\/div>\n\n\n\n<hr class=\"wp-block-vivid360-separator has-text-color has-background has-medium-gray-background-color has-medium-gray-color full-page-width\" style=\"height:0\"\/>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><link rel='stylesheet' id='vivid360-card-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/card\/css\/style.min.css?ver=1781887228' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-card a6a89c17a-e9cd-44b0-83e7-717b76ebc063 vivid360-block-card has-text-align-left hasBoxShadow card-horizontal has-primary-dark-color full-page-width\" style=\"--media-width: 68px;--mobile-media-width: 68px;border-width:0px;border-style:;border-radius:0;\"><div class=\"card-media \"><figure class=\"ratio-1-1 ratio-1-1-mobile\"><picture><source media=\"(max-width: 767px)\" data-srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq_Dosage-and-Administration_Icon_KO@2x_mob.png?w=767\"\/><source media=\"(min-width: 768px) and (max-width: 1440px)\" data-srcset=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq_Dosage-and-Administration_Icon_KO@2x_new.png?w=1440\"\/><img decoding=\"async\" width=\"68\" height=\"358\" data-src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq_Dosage-and-Administration_Icon_KO@2x_new.png\" loading=\"lazy\" src=\"https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/uploads\/sites\/168\/2026\/06\/RotaTeq_Dosage-and-Administration_Icon_KO@2x_new.png\" alt=\"\"\/><\/picture><\/figure><\/div><div class=\"card-content\"><div class=\"card-content-wrap\"><h4 class=\"card-header fontWeightBold\"><strong><strong>Dosing and administration<\/strong><\/strong><\/h4><div class=\"card-desc has-regular-font-size\">\n<p class=\"has-dark-text-color has-text-color\">Review the dosing schedule and administration of RotaTeq.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p class=\"has-primary-light-color has-text-color\"><a href=\"https:\/\/www.merckvaccines.com\/rotateq\/dosage-and-administration\/\" aria-label=\"#\">Learn more about dosing<\/a><\/p>\n<\/div><\/div><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><\/div>\n<\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<div class=\"vivid360-heading\" id=\"a7e56579a-25ff-4d5b-aa3c-5356300ebe49\"><h3 class=\"has-primary-light-color content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h3FontSizeDesktop);--tabletFontSize:var(--h3FontSizeDesktop);--mobileFontSize:var(--h3FontSizeMobile);--desktopLineHeightSize:var(--h3LineHeightDesktop);--tabletLineHeightSize:var(--h3LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>References<\/strong><\/h3><\/div>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n<link rel='stylesheet' id='vivid360-list-parent-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/list-parent\/css\/style.css?ver=1764595895' media='all' \/>\n\n<div class=\"vivid-block-list2 content-width isBold \">\n<ol style=\"--listBulletColor:#333\" class=\"list-bullet-color\">\n<li class=\"has-small-font-size\"><em>Rotarix<\/em>. Prescribing information. GSK; 2024.<\/li>\n\n\n\n<li class=\"has-small-font-size\">Dennis AF, McDonald SM, Payne DC, et al. Molecular epidemiology of contemporary G2P[4] human rotaviruses cocirculating in a single U.S. community: Footprints of a globally transitioning genotype. <em>J Virol<\/em>. 2014;88(7):3789-3801.<\/li>\n\n\n\n<li class=\"has-small-font-size\">Matthijnssens J, Van Ranst M. Genotype constellation and evolution of group A rotaviruses infecting humans. <em>Curr Opin Virol<\/em>. 2012;2(4):426-433.<\/li>\n\n\n\n<li class=\"has-small-font-size\">Diallo AO, Wikswo ME, Sulemana I, et al. Rotavirus vaccine effectiveness against severe acute gastroenteritis: 2009\u20132022. <em>Pediatrics<\/em>. 2024;154(4):e2024066879. doi:10.1542\/peds.2024-066879<\/li>\n<\/ol>\n<\/div>\n\n\n<link rel='stylesheet' id='vivid360-modal-css-css' href='https:\/\/www.merckvaccines.com\/rotateq\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/modal\/css\/style.min.css?ver=1771242728' media='all' \/>\n\n<div class=\"wp-block-vivid360-modal\"><div><div class=\"vivid360-modal-block-container is-style-passive-modal-two-btn\"><div class=\"vivid360-modal-trigger-container\"><span id=\"inlineTrigger\" role=\"link\" data-design-module=\"modal\" data-design-category=\"link\" class=\"vivid360-modal-trigger vivid360-modal-trigger-hide\">ExternalSitePopup<\/span><\/div><div class=\"vivid360-modal-container null\"><div class=\"vivid360-modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"modal-title\"><div class=\"vivid360-modal-content-area\"><a class=\"vivid360-modal-close-modal-span\" role=\"button\" aria-label=\"modal popup close\"><i class=\"icon-close\"><\/i><\/a><div class=\"modal-flex-container\"><div class=\"vivid360-modal-label-container  title-left\" style=\"--titleColor:#00857c\"><h2>By clicking on this link, you will be leaving Merck Vaccines.<\/h2><\/div><div class=\"vivid360-modal-content-container has-regular-font-size\"><\/div><div class=\"vivid360-modal-button-container desktop-container\"><div class=\"vivid360-button-block\"><a class=\"btn secondary secondary-regular btn-confirm  vivid360-modal-dismiss-button\" role=\"button\" aria-label=\"Button 1\" style=\"font-size:14px;color:#00857c\" href=\"#!\" title=\"Cancel\" target=\"_self\" rel=\"noopener\" data-design-category=\"button\" data-design-label=\"Cancel\" data-design-module=\"element\">Cancel<\/a><\/div><div class=\"vivid360-button-block\"><a class=\"btn primary-alternate primary-alternate-regular btn-dismissive  vivid360-modal-action-button\" 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