M-M-R®II vaccine has two storage options

Flexible storage and handling

M-M-R®II vaccine has two storage options:

With M-M-R®II, you have the option of storing it in the fridge or freezer for later use. The M-M-R®II vaccine contains active ingredients and must be:

M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live) Can Be Stored in the Fridge or Freezer for Later Use

Storage

  • Stored between -58oF and +46oF (-50oC to +8oC)
  • Kept away from exposure to light
  • Checked to ensure temperatures are not colder than -58oF (-50oC) when using dry ice
  • Refrigerated at 36oF to 46oF (2oC to 8oC) before reconstituting the lyophilized vaccine
  • Administered as soon as possible after reconstitutiona

aIf not administered immediately, reconstituted vaccine may be stored between 36oF to 46oF (2oC to 8oC), protected from light for up to 8 hours. Discard if not used within 8 hours. Store accompanying diluent in the refrigerator at 36oF to 46oF (2oC to 8oC) or at room temperature 68oF to 77oF (20oC to 25oC). DO NOT FREEZE the diluent.

M-M-R®II can be reconstituted in 3 steps:

Review Handling Information for M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live) Which Can Be Reconstituted in Three Steps

Handling

  1. Withdraw the entire volume of the supplied diluentb from its vial and inject into lyophilized vaccine vial
  2. Agitate to dissolve completely and discard if the lyophilized vaccine cannot be dissolved
  3. Visually inspect the vaccine before and after reconstitution to ensure it is a clear, yellow liquid

bUse only the diluent supplied with the vaccine to ensure it remains active.

Questions?

If you have questions about the condition of the vaccine at the time of delivery, you should immediately place the vaccine in the recommended storage and call the Merck Vaccine Customer Care Center at 877.VAX.MERCK (877.829.6372).

For general questions, please contact the Merck Vaccine Customer Helpline at 800.MERCK.90 (800.637.2590), Monday through Friday, 8:00 am to 7:00 pm ET.


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Clinical Data for M-M-R®II (Measles, Mumps, & Rubella Virus Vaccine Live)

Clinical Data

Explore the robust coverage M-M-R®II offers your pediatric patients starting after their first dose.1

Dosage and Administration for M-M-R®II (Measles, Mumps, & Rubella Virus Vaccine Live)

Dosage and Administration

Discover the dosing regimen and administration of M-M-R®II.

ref1

Reference

  1. Marin M, Broder KR, Temte JL, et al. Centers for Disease Control and Prevention. Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2010;59(3):1-12.

Indications and Usage for M-M-R®II

  • M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live) is a vaccine indicated for active immunization for the prevention of measles, mumps, and rubella in individuals 12 months of age or older.
  • The first dose of M-M-R®II is administered at 12 to 15 months of age and the second dose of M-M-R®II is administered at 4 to 6 years of age.

Selected Safety Information for M-M-R®II

  • M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live) is contraindicated in certain individuals, including those with: a history of hypersensitivity to any component of the vaccine, including gelatin; a history of anaphylactic reaction to neomycin; individuals who are immunodeficient or immunosuppressed due to disease or medical therapy; an active febrile illness; active untreated tuberculosis; or those who are pregnant or are planning to become pregnant within the next month.
  • Due caution should be employed in administration of M-M-R®II to persons with: a history of febrile seizure or family history of febrile seizures; immediate-type hypersensitivity reactions to eggs; thrombocytopenia.
  • Vaccination should be deferred in individuals with a family history of congenital or hereditary immunodeficiency until the individual’s immune status has been evaluated and the individual has been found to be immunocompetent.
  • Immune globulins (IG) and other blood products should not be given concurrently with M-M-R®II. The ACIP has specific recommendations for intervals between administration of antibody-containing products and live virus vaccines.
  • The following adverse reactions have been identified during clinical trials or reported during post-approval use of M-M-R®II or its components: fever, headache, dizziness, rash, injection-site reactions, febrile convulsions, anaphylaxis and anaphylactoid reactions, arthritis, thrombocytopenia, encephalitis and encephalopathy.

DOSAGE AND ADMINISTRATION

  • FOR SUBCUTANEOUS USE ONLY.
  • M-M-R®II vaccine can be administered concurrently with other live viral vaccines. If not given concurrently, M-M-R®II vaccine should be given one month before or one month after administration of other live viral vaccines to avoid potential for immune interference.

Before administering M-M-R®II, please read the accompanying Prescribing Information. The Patient Information also is available.

Indications and Usage for M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live)

  • M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live) is a vaccine indicated for active immunization for the prevention of measles, mumps, and rubella in individuals 12 months of age or older.
  • The first dose of M-M-R®II is administered at 12 to 15 months of age and the second dose of M-M-R®II is administered at 4 to 6 years of age.

M-M-R®II is a vaccine indicated for active immunization for the prevention of measles, mumps

M-M-R®II is a vaccine indicated for active immunization for the prevention of measles, mumps, and rubella in individuals 12 months of age or older. The first dose of M-M-R®II is administered at 12 to 15 months of age and the second dose of M-M-R®II is administered at 4 to 6 years of age.

Selected Safety Information for M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live)

  • M-M-R®II (Measles, Mumps, and Rubella Virus Vaccine Live) is contraindicated in certain individuals, including those with: a history of hypersensitivity to any component of the vaccine, including gelatin; a history of anaphylactic reaction to neomycin; individuals who are immunodeficient or immunosuppressed due to disease or medical therapy; an active febrile illness; active untreated tuberculosis; or those who are pregnant or are planning to become pregnant within the next month.
  • Due caution should be employed in administration of M-M-R®II to persons with: a history of febrile seizure or family history of febrile seizures; immediate-type hypersensitivity reactions to eggs; thrombocytopenia.
  • Vaccination should be deferred in individuals with a family history of congenital or hereditary immunodeficiency until the individual’s immune status has been evaluated and the individual has been found to be immunocompetent.
  • Immune globulins (IG) and other blood products should not be given concurrently with M-M-R®II. The ACIP has specific recommendations for intervals between administration of antibody-containing products and live virus vaccines.
  • The following adverse reactions have been identified during clinical trials or reported during post-approval use of M-M-R®II or its components: fever, headache, dizziness, rash, injection-site reactions, febrile convulsions, anaphylaxis and anaphylactoid reactions, arthritis, thrombocytopenia, encephalitis and encephalopathy.

DOSAGE AND ADMINISTRATION

  • FOR SUBCUTANEOUS USE ONLY.
  • M-M-R®II vaccine can be administered concurrently with other live viral vaccines. If not given concurrently, M-M-R®II vaccine should be given one month before or one month after administration of other live viral vaccines to avoid potential for immune interference.

Before administering M-M-R®II, please read the accompanying Prescribing Information. The Patient Information also is available.

M-M-R®II is contraindicated in certain individuals, including those with: a history of

M-M-R®II is contraindicated in certain individuals, including those with: a history of hypersensitivity to any component of the vaccine, including gelatin; a history of anaphylactic reaction to neomycin; individuals who are immunodeficient or immunosuppressed due to disease or medical therapy; an active febrile illness; active untreated tuberculosis; or those

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