{"id":1148,"date":"2023-08-08T17:09:05","date_gmt":"2023-08-08T17:09:05","guid":{"rendered":"https:\/\/www.merckvaccines.com\/varivax\/?page_id=1148"},"modified":"2025-10-28T10:47:48","modified_gmt":"2025-10-28T10:47:48","slug":"diluent-reconstitution","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/varivax\/diluent-reconstitution\/","title":{"rendered":"Reconstitution"},"content":{"rendered":"<link rel='stylesheet' id='vivid360-hero-css-css' href='https:\/\/www.merckvaccines.com\/varivax\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/hero\/css\/style.min.css?ver=1770880337' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-hero\"><div class=\"vivid360-hero-container align-left align-middle ratio-70-30 horizontal mobile text-align-left has-black-color is-default-style mobile-is-default-style mobile-uses-custom-styles\" style=\"border-width:0;border-style:solid;border-top-left-radius:0;border-top-right-radius:0;border-bottom-right-radius:0;border-bottom-left-radius:0;--minHeight:244px;--mobileMinHeight:154px\"><div class=\"wide_screens hidden\" data-value=\"stretch\"><\/div><picture><source media=\"(max-width: 767px)\" srcset=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/Mobile-2.png?w=767\"\/><source media=\"(min-width: 768px) and (max-width: 1024px)\" srcset=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/Mobile-2.png?w=1024\"\/><source media=\"(min-width: 1025px) and (max-width:1440px)\" srcset=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/VARIVAX_4_Clinical-Data_hero_banner_1128px_v5@2x-1.png?w=1440\"\/><img decoding=\"async\" width=\"2257\" height=\"485\" loading=\"lazy\" data-src=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/VARIVAX_4_Clinical-Data_hero_banner_1128px_v5@2x-1.png?w=1920\" src=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/VARIVAX_4_Clinical-Data_hero_banner_1128px_v5@2x-1.png?w=1920\" alt=\"\" class=\"hero-image\" style=\"--desktop-focal-x:98%;--desktop-focal-y:25%;--mobile-focal-x:50%;--mobile-focal-y:50%;--tablet-focal-x:50%;--tablet-focal-y:50%\"\/><div class=\"capoverlay-container-mobile right-bottom show  hide_mobile isMobileOverlayChecked label\" style=\"--top-margin:;--bottom-margin:;--left-margin:;--right-margin:\"><div class=\"overlay-caption-schema\">Actor Portrayal<\/div><\/div><\/picture><div class=\"hero-wrapper\"><div class=\"hero-content\"><h1 style=\"--headlineFontSize:36px;--headlineFontSizeTablet:36px;--headlineFontSizeMobile:24px;--headlineLineHeight:45px;--headlineLineHeightTablet:45px;--headlineLineHeightMobile:30px\" class=\"hero-title fontWeightRegular\">Reconstitute VARIVAX\u00ae (Varicella Virus Vaccine Live) using a<strong> prefilled diluent syringe<\/strong><\/h1><p class=\"hero-description\"><\/p><div class=\"hero-btn-group\">\n<p><\/p>\n<\/div><div class=\"hero-caption\"><\/div><\/div><\/div><\/div><div class=\"hero-caption-2mobile\"><\/div><\/div>\n\n\n<link rel='stylesheet' id='vivid360-spacer-css-css' href='https:\/\/www.merckvaccines.com\/varivax\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/spacer\/css\/style.min.css?ver=1770880337' media='all' \/>\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:15%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:70%\"><link rel='stylesheet' id='vivid360-video-module-css-css' href='https:\/\/www.merckvaccines.com\/varivax\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/video-module\/css\/style.min.css?ver=1770880337' media='all' \/>\n\n<div id=\"\" class=\"wp-block-vivid360-video-module vivid360-block-video-module video-module-center full-page-width\"><div class=\"video-wrapper\"><div data-tracking-video=\"6366806185112\" class=\"vivid360-block-video-module-video-content\"><div><video id=\"video-block\" data-design-category=\"Video\" data-account=\"1905768940001\" data-player=\"default\" data-embed=\"default\" controls data-video-id=\"6366806185112\" data-playlist-id=\"\" data-application-id=\"\" class=\"vjs-fluid video-js\" data-jobcode=\"US-VVX-00062\" aria-labelledby=\"video_label\" aria-describedby=\"video_description\"><\/video><\/div><\/div><div id=\"video_label\" hidden>BrightCove Video<\/div><div id=\"video_description\" aria-live=\"polite\" role=\"caption\" hidden><\/div><figure class=\"text-align-left\"><figcaption><\/figcaption><\/figure><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:15%\"><\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Attach a needle to the prefilled syringe.<\/strong><\/p>\n\n\n<link rel='stylesheet' id='vivid360-image-css-css' href='https:\/\/www.merckvaccines.com\/varivax\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/image\/css\/style.min.css?ver=1776931356' media='all' \/>\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2023\/11\/reconstitution-img-1.png\" alt=\"Reconstitution of Varivax Using a Pre-Filled Diluent Syringe\" class=\"wp-image-1747  style-noshadow   \" width=\"256\" height=\"154\" title=\"\" style=\"height:154px;width:256px\"\/><\/figure><\/div><\/div>\n\n\n\n<p>Visually inspect the vaccine for discoloration. <strong>Slowly inject the entire volume <\/strong>of sterile diluent prefilled syringe into the lyophilized vaccine vial. <strong>Gently agitate to dissolve completely.<\/strong> Discard if the lyophilized<br>vaccine cannot be dissolved. Do not use the product if particulates are present or if it appears   discolored.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p>Before reconstitution, the lyophilized vaccine is a white compact crystalline plug. VARIVAX, when reconstituted, is a clear, colorless to pale yellow liquid.<\/p>\n\n\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2023\/11\/reconstitution-img-3.png\" alt=\"How to Insert the Diluent Syringe Into Lyophilized Vaccine Vial\" class=\"wp-image-1748  style-noshadow   \" width=\"193\" height=\"234\" title=\"\" style=\"height:234px;width:193px\"\/><\/figure><\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p>Visually inspect the vaccine again for discoloration. <strong>Withdraw and administer the entire volume of      the reconstituted vaccine immediately.<\/strong><\/p>\n\n\n\n<div class=\"wp-block-vivid360-image\"><div class=\"img-container \"><figure class=\"wp-block-vivid360-image is-style-default aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/CAT_PFS-Diluent_Step_3_Figure_FINAL_HI_9e3755.png\" alt=\"How to Withdraw the Reconstituted Vaccine\" class=\"wp-image-1971  style-noshadow   \" width=\"158\" height=\"280\" title=\"\" style=\"height:280px;width:158px\" srcset=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/CAT_PFS-Diluent_Step_3_Figure_FINAL_HI_9e3755.png 579w, https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/CAT_PFS-Diluent_Step_3_Figure_FINAL_HI_9e3755.png?resize=170,300 170w\" sizes=\"auto, (max-width: 158px) 100vw, 158px\" \/><\/figure><\/div><\/div>\n\n\n\n<p>Discard if reconstituted vaccine is not used within 30 minutes. Do not freeze reconstituted vaccine. Do not combine VARIVAX with any other vaccine through reconstitution or mixing.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"wp-block-vivid360-button-parent btn-block-container content-width button-justify-center\"><link rel='stylesheet' id='vivid360-button-block-css-css' href='https:\/\/www.merckvaccines.com\/varivax\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/button\/css\/style.min.css?ver=1770880337' media='all' \/>\n<link rel='stylesheet' id='vivid360-button-parent-block-css-css' href='https:\/\/www.merckvaccines.com\/varivax\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/button-parent\/css\/style.min.css?ver=6.8.5' media='all' \/>\n\n<div class=\"vivid360-button-block fullWidth-mobile\"><a class=\"btn primary primary-regular\" role=\"button\" style=\"font-size:14px;letter-spacing:0.86px;border-radius:4px;border-style:solid;justify-content:center;text-align:center;width:100%\" href=\"https:\/\/www.merckvaccines.com\/varivax\/wp-content\/uploads\/sites\/81\/2025\/10\/US-MMR-00601_MMRV-Family-Storage-Reconstitution-Leave-Behind_v7_CORAL-1.pdf\" title=\"Get reconstitution PDF\" target=\"_blank\" rel=\"noopener\" data-design-category=\"button\" data-design-label=\"Get reconstitution PDF\" data-design-module=\"element\" data-event-name=\"element_click\">Get reconstitution PDF<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Attach a needle to the prefilled syringe. Visually inspect the vaccine for discoloration. Slowly inject the entire volume of sterile diluent prefilled&#8230;<\/p>\n","protected":false},"author":664,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[224],"ga4_page_businessunit":[232],"ga4_page_campaign":[],"ga4_page_content_purpose":[245],"ga4_page_customer_journey_stage":[293],"ga4_page_customer_specialty":[338],"ga4_page_experience":[],"ga4_page_indication":[495],"ga4_page_material_intent":[497],"ga4_page_product":[688],"ga4_page_region":[794],"ga4_page_therapeuticarea":[846],"class_list":["post-1148","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Reconstitute VARIVAX\u00ae (Varicella Virus Vaccine Live) with a Prefilled Diluent 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