{"id":87,"date":"2024-06-26T13:48:27","date_gmt":"2024-06-26T13:48:27","guid":{"rendered":"https:\/\/www.merckvaccines.com\/vaxneuvance\/?page_id=87"},"modified":"2026-02-23T09:12:20","modified_gmt":"2026-02-23T09:12:20","slug":"dosage-administration","status":"publish","type":"page","link":"https:\/\/www.merckvaccines.com\/vaxneuvance\/dosage-administration\/","title":{"rendered":"Dosage administration"},"content":{"rendered":"\n\n
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Guidance on pediatric dosage and administration of VAXNEUVANCE<\/strong><\/h1>

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VAXNEUVANCE\u2014a CDC, AAP, and AAFP recommended option for all of your appropriate pediatric patients\u2014is administered as a 4-dose series1-3<\/sup><\/strong><\/h2><\/div>\n\n\n\n
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<\/span>Completion of the 4th dose is important to achieve and maintain serotype-specific immune responses.<\/mark>4<\/sup><\/strong><\/span><\/p><\/blockquote><\/div>\n\n\n\n

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CDC recommendation on interchangeability1<\/sup><\/strong><\/h3>
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VAXNEUVANCE is a CDC recommended option for a 4-dose series or for completion of a 4-dose series initiated with another PCV.<\/p>\n\n\n

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a<\/sup>Dose 1 may be given as early as 6 weeks of age.
b<\/sup>The recommended interval between doses is 4 to 8 weeks.
c<\/sup>The 4th dose should be administered at approximately 12 through 15 months of age and at least 2 months after the 3rd dose.<\/p>\n\n\n\n

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How to administer VAXNEUVANCE<\/strong><\/h3><\/div>\n\n\n\n
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VAXNEUVANCE is for intramuscular injection only. Each dose is 0.5 mL.<\/p><\/div><\/div>\n\n\n\n

Hold the prefilled syringe horizontally and shake vigorously immediately prior to use to obtain an opalescent suspension. Do not use the vaccine if it cannot be resuspended. Do not use if particulate matter or discoloration is observed.<\/p><\/div><\/div>\n\n\n\n

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